Differential impact of cytochrome 2C9 allelic variants on clopidogrel-mediated platelet inhibition determined by five different platelet function tests - Gremmel, Thomas; Kopp, Christoph W.; Seidinger, Daniela; Koppensteiner, Renate; Panzer, Simon; Sunder-Plassmann, Raute; Mannhalter, Christine; Steiner, Sabine (International journal of cardiology, 2013)
Keywords: Aged; Alleles; Aryl Hydrocarbon Hydroxylases - genetics; Biological and medical sciences; Cardiology. Vascular system; Cardiovascular; Clopidogrel; CYP2C9; Cytochrome P-450 CYP2C9; Female; Genetic Variation - genetics; Heart; Humans; Male; Medical sciences; Middle Aged; Platelet Aggregation - drug effects; Platelet Aggregation - genetics; Platelet Aggregation Inhibitors - pharmacology; Platelet function testing; Platelet Function Tests - methods; Platelet Function Tests - standards; Polymorphism, Genetic - drug effects; Polymorphism, Genetic - genetics; Ticlopidine - analogs & derivatives; Ticlopidine - pharmacology; CYP2C9; Clopidogrel; Platelet function testing; Enzyme; Cytochrome P450; Cardiovascular disease; Medical screening; Antiplatelet agent; Variant; Platelet; Platelet function; Antithrombotic agent; Inhibition; Thienopyridine derivative; Cardiology