Chemometric analysis of the global pattern of volatile organic compounds in the exhaled breath of patients with COVID-19, post-COVID and healthy subjects. Proof of concept for post-COVID assessment

• Published in: Talanta (Oxford) Vol. 236; p. 122832
• Main Authors: Zamora-Mendoza, Blanca Nohemí, Díaz de León-Martínez, Lorena, Rodríguez-Aguilar, Maribel, Mizaikoff, Boris, Flores-Ramírez, Rogelio
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.01.2022
• Subjects: Chemometric data analysis; chemometrics; COVID-19; COVID-19 infection; Cross-Sectional Studies; discriminant analysis; electronic nose; Electronic nose system; Exhaled breath analysis; Healthy Volunteers; Humans; Post-COVID syndrome; principal component analysis; SARS-CoV-2; support vector machines; Volatile Organic Compounds; COVID-19; Volatile organic compounds; Exhaled breath analysis; Electronic nose system; Post-COVID syndrome; Chemometric data analysis

The objective of this research was to evaluate the application of an electronic nose and chemometric analysis to discriminate volatile organic compounds between patients with COVID-19, post-COVID syndrome and controls in exhaled breath samples. A cross-sectional study was performed on 102 exhaled br...