Biologics: the next-generation therapeutics for analgesia?

• Published in: Expert review of neurotherapeutics Vol. 11; no. 11; pp. 1653 - 1658
• Main Authors: Hatcher, Jonathan P, Chessell, Iain P, Hughes, Jane P
• Format: Journal Article
• Language: English
• Published: England Taylor & Francis 01.11.2011; Expert Reviews Ltd; Informa Healthcare
• Subjects: Analgesia; Analgesics - pharmacology; Animals; Biological Products - pharmacology; biologics; Chronic pain; Drug therapy; Health aspects; Humans; interleukin-6; nerve growth factor; pain; Pain - drug therapy; Physiological aspects; Tumor necrosis factor; United Kingdom

There is a huge unmet need for novel medicines for the treatment of chronic pain. In this article, we briefly examine some of the issues associated with traditional approaches to the treatment of these conditions. We go on to present some of the current evidence for three of the most advanced approa...