Indolic uremic solutes increase tissue factor production in endothelial cells by the aryl hydrocarbon receptor pathway - Gondouin, Bertrand; Cerini, Claire; Dou, Laetitia; Sallée, Marion; Duval-Sabatier, Ariane; Pletinck, Anneleen; Calaf, Raymond; Lacroix, Romaric; Jourde-Chiche, Noémie; Poitevin, Stéphane; Arnaud, Laurent; Vanholder, Raymond; et al. (Kidney international, 2013)
Keywords: Adult; Aged; Aged, 80 and over; aryl hydrocarbon receptor; Benzoquinones - pharmacology; Cardiology and cardiovascular system; Case-Control Studies; Cells, Cultured; Dioxins - pharmacology; Endothelium, Vascular - cytology; Endothelium, Vascular - drug effects; Endothelium, Vascular - metabolism; Female; Human health and pathology; Humans; In Vitro Techniques; Indican - metabolism; Indican - pharmacology; Indoleacetic Acids - metabolism; Indoleacetic Acids - pharmacology; Lactams, Macrocyclic - pharmacology; Leukocytes, Mononuclear - cytology; Leukocytes, Mononuclear - drug effects; Leukocytes, Mononuclear - metabolism; Life Sciences; Male; Middle Aged; Polymerase Chain Reaction; Receptors, Aryl Hydrocarbon - antagonists & inhibitors; Receptors, Aryl Hydrocarbon - drug effects; Receptors, Aryl Hydrocarbon - metabolism; Renal Insufficiency, Chronic - metabolism; RNA, Small Interfering - pharmacology; Signal Transduction - drug effects; Signal Transduction - physiology; Thromboplastin - metabolism; Tissue Array Analysis; tissue factor; Umbilical Veins - cytology; Umbilical Veins - drug effects; Umbilical Veins - metabolism; Up-Regulation - drug effects; Up-Regulation - physiology; uremic solutes; Urology and Nephrology; tissue factor; uremic solutes; aryl hydrocarbon receptor