Gram-negative bacterial endocarditis in adults: state-of-the-heart
Gram-negative endocarditis due to HACEK bacteria (Haemophilus species, Actinobacillus, Cardiobacterium, Eikenella and Kingella species) and non-HACEK organisms is an infrequent occurrence but is associated with significant morbidity and mortality. Traditionally, non-HACEK Gram-negative endocarditis...
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| Published in | Expert review of anti-infective therapy Vol. 8; no. 8; pp. 879 - 885 |
|---|---|
| Main Authors | , , |
| Format | Journal Article |
| Language | English |
| Published |
England
Taylor & Francis
01.08.2010
Expert Reviews Ltd Informa Healthcare |
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| Abstract | Gram-negative endocarditis due to HACEK bacteria (Haemophilus species, Actinobacillus, Cardiobacterium, Eikenella and Kingella species) and non-HACEK organisms is an infrequent occurrence but is associated with significant morbidity and mortality. Traditionally, non-HACEK Gram-negative endocarditis has been associated with injection drug use. However, emerging data from more contemporary cohorts suggest changing epidemiology and risk factors for Gram-negative endocarditis, necessitating an updated review of this subject. Moreover, optimal management, including the need for surgical intervention, and strategies for the prevention of Gram-negative endocarditis need to be revisited. |
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| AbstractList | Gram-negative endocarditis due to HACEK bacteria (Haemophilus species, Actinobacillus, Cardiobacterium, Eikenella and Kingella species) and non-HACEK organisms is an infrequent occurrence but is associated with significant morbidity and mortality. Traditionally, non-HACEK Gram-negative endocarditis has been associated with injection drug use. However, emerging data from more contemporary cohorts suggest changing epidemiology and risk factors for Gram-negative endocarditis, necessitating an updated review of this subject. Moreover, optimal management, including the need for surgical intervention, and strategies for the prevention of Gram-negative endocarditis need to be revisited. Gram-negative endocarditis due to HACEK bacteria (Haemophilus species, Actinobacillus, Cardiobacterium, Eikenella and Kingella species) and non-HACEK organisms is an infrequent occurrence but is associated with significant morbidity and mortality. Traditionally, non-HACEK Gram-negative endocarditis has been associated with injection drug use. However, emerging data from more contemporary cohorts suggest changing epidemiology and risk factors for Gram-negative endocarditis, necessitating an updated review of this subject. Moreover, optimal management, including the need for surgical intervention, and strategies for the prevention of Gram-negative endocarditis need to be revisited.Gram-negative endocarditis due to HACEK bacteria (Haemophilus species, Actinobacillus, Cardiobacterium, Eikenella and Kingella species) and non-HACEK organisms is an infrequent occurrence but is associated with significant morbidity and mortality. Traditionally, non-HACEK Gram-negative endocarditis has been associated with injection drug use. However, emerging data from more contemporary cohorts suggest changing epidemiology and risk factors for Gram-negative endocarditis, necessitating an updated review of this subject. Moreover, optimal management, including the need for surgical intervention, and strategies for the prevention of Gram-negative endocarditis need to be revisited. |
| Audience | Academic |
| Author | Raza, Sania S Sohail, Muhammad R Sultan, Omer W |
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| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/20695743$$D View this record in MEDLINE/PubMed |
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| SubjectTerms | Actinobacillus Adult Adults Anti-Bacterial Agents - therapeutic use bacilli Bacteria Care and treatment Diagnosis endocarditis Endocarditis, Bacterial Endocarditis, Bacterial - drug therapy Endocarditis, Bacterial - epidemiology Endocarditis, Bacterial - microbiology Endocarditis, Bacterial - surgery Epidemiology Gram-negative Gram-Negative Bacteria - classification Gram-Negative Bacteria - drug effects HACEK Haemophilus Health aspects Health Planning Guidelines Humans management Mortality recommendations Risk Factors United States |
| Title | Gram-negative bacterial endocarditis in adults: state-of-the-heart |
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