Guideline on antiplatelet and anticoagulation management in cardiac surgery

This document presents a professional view of evidence-based recommendations around the issues of antiplatelet and anticoagulation management in cardiac surgery. It was prepared by the Audit and Guidelines Committee of the European Association for Cardio-Thoracic Surgery (EACTS). We review the follo...

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Published inEuropean journal of cardio-thoracic surgery Vol. 34; no. 1; pp. 73 - 92
Main Authors Dunning, Joel, Versteegh, Michel, Fabbri, Alessandro, Pavie, Alain, Kolh, Philippe, Lockowandt, Ulf, Nashef, Samer A.M.
Format Journal Article Web Resource
LanguageEnglish
Published Amsterdam Elsevier Science B.V 01.07.2008
Elsevier Science
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Abstract This document presents a professional view of evidence-based recommendations around the issues of antiplatelet and anticoagulation management in cardiac surgery. It was prepared by the Audit and Guidelines Committee of the European Association for Cardio-Thoracic Surgery (EACTS). We review the following topics: evidence for aspirin, clopidogrel and warfarin cessation prior to cardiac surgery; perioperative interventions to reduce bleeding including the use of aprotinin and tranexamic acid; the use of thromboelastography to guide blood product usage; protamine reversal of heparin; the use of factor VIIa to control severe bleeding; anticoagulation after mechanical, tissue valve replacement and mitral valve repair; the use of antiplatelets and clopidogrel after cardiac surgery to improve graft patency and reduce thromboembolic complications and thromboprophylaxis in the postoperative period. This guideline is subject to continuous informal review, and when new evidence becomes available. The formal review date will be at 5 years from publication (September 2013).
AbstractList This document presents a professional view of evidence-based recommendations around the issues of antiplatelet and anticoagulation management in cardiac surgery. It was prepared by the Audit and Guidelines Committee of the European Association for Cardio-Thoracic Surgery (EACTS). We review the following topics: evidence for aspirin, clopidogrel and warfarin cessation prior to cardiac surgery; perioperative interventions to reduce bleeding including the use of aprotinin and tranexamic acid; the use of thromboelastography to guide blood product usage; protamine reversal of heparin; the use of factor VIIa to control severe bleeding; anticoagulation after mechanical, tissue valve replacement and mitral valve repair; the use of antiplatelets and clopidogrel after cardiac surgery to improve graft patency and reduce thromboembolic complications and thromboprophylaxis in the postoperative period. This guideline is subject to continuous informal review, and when new evidence becomes available. The formal review date will be at 5 years from publication (September 2013).
This document presents a professional view of evidence-based recommendations around the issues of antiplatelet and anticoagulation management in cardiac surgery. It was prepared by the Audit and Guidelines Committee of the European Association for Cardio-Thoracic Surgery (EACTS). We review the following topics: evidence for aspirin, clopidogrel and warfarin cessation prior to cardiac surgery; perioperative interventions to reduce bleeding including the use of aprotinin and tranexamic acid; the use of thromboelastography to guide blood product usage; protamine reversal of heparin; the use of factor VIIa to control severe bleeding; anticoagulation after mechanical, tissue valve replacement and mitral valve repair; the use of antiplatelets and clopidogrel after cardiac surgery to improve graft patency and reduce thromboembolic complications and thromboprophylaxis in the postoperative period. This guideline is subject to continuous informal review, and when new evidence becomes available. The formal review date will be at 5 years from publication (September 2013).This document presents a professional view of evidence-based recommendations around the issues of antiplatelet and anticoagulation management in cardiac surgery. It was prepared by the Audit and Guidelines Committee of the European Association for Cardio-Thoracic Surgery (EACTS). We review the following topics: evidence for aspirin, clopidogrel and warfarin cessation prior to cardiac surgery; perioperative interventions to reduce bleeding including the use of aprotinin and tranexamic acid; the use of thromboelastography to guide blood product usage; protamine reversal of heparin; the use of factor VIIa to control severe bleeding; anticoagulation after mechanical, tissue valve replacement and mitral valve repair; the use of antiplatelets and clopidogrel after cardiac surgery to improve graft patency and reduce thromboembolic complications and thromboprophylaxis in the postoperative period. This guideline is subject to continuous informal review, and when new evidence becomes available. The formal review date will be at 5 years from publication (September 2013).
Summary This document presents a professional view of evidence-based recommendations around the issues of antiplatelet and anticoagulation management in cardiac surgery. It was prepared by the Audit and Guidelines Committee of the European Association for Cardio-Thoracic Surgery (EACTS). We review the following topics: evidence for aspirin, clopidogrel and warfarin cessation prior to cardiac surgery; perioperative interventions to reduce bleeding including the use of aprotinin and tranexamic acid; the use of thromboelastography to guide blood product usage; protamine reversal of heparin; the use of factor VIIa to control severe bleeding; anticoagulation after mechanical, tissue valve replacement and mitral valve repair; the use of antiplatelets and clopidogrel after cardiac surgery to improve graft patency and reduce thromboembolic complications and thromboprophylaxis in the postoperative period. This guideline is subject to continuous informal review, and when new evidence becomes available. The formal review date will be at 5 years from publication (September 2013).
Author Dunning, Joel
Versteegh, Michel
Nashef, Samer A.M.
Fabbri, Alessandro
Pavie, Alain
Lockowandt, Ulf
Kolh, Philippe
Author_xml – sequence: 1
  givenname: Joel
  surname: Dunning
  fullname: Dunning, Joel
  organization: Department of Cardiothoracic Surgery, James Cook University Hospital, Middlesbrough, UK
– sequence: 2
  givenname: Michel
  surname: Versteegh
  fullname: Versteegh, Michel
  organization: Department of Cardiothoracic Surgery, Leiden University Medical Center, Leiden, Netherlands
– sequence: 3
  givenname: Alessandro
  surname: Fabbri
  fullname: Fabbri, Alessandro
  organization: Department of Cardiac Surgery, Vicenzo Hospital, Italy
– sequence: 4
  givenname: Alain
  surname: Pavie
  fullname: Pavie, Alain
  organization: Institute of Cardiology, La Pitié-Salpêtrière Hospital, Paris, France
– sequence: 5
  givenname: Philippe
  surname: Kolh
  fullname: Kolh, Philippe
  organization: Department of Cardiothoracic Surgery, University Hospital of Liege, Liege, Belgium
– sequence: 6
  givenname: Ulf
  surname: Lockowandt
  fullname: Lockowandt, Ulf
  organization: Department of Cardiothoracic Surgery, Karolinska University Hospital, Stockholm, Sweden
– sequence: 7
  givenname: Samer A.M.
  surname: Nashef
  fullname: Nashef, Samer A.M.
  organization: Department of Cardiothoracic Surgery, Papworth Hospital CB23 3RE, Cambridge, UK
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Issue 1
Keywords Antiplatelet therapy
Thoracic surgery
Anticoagulation therapy
Evidence-based medicine
Guidelines
Evidence-based practice
Thorax
Cardiac surgery
Antiplatelet agent
Recommendation
Chemotherapy
Treatment
Clinical management
Circulatory system
Cardiology
Pneumology
Language English
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PublicationTitle European journal of cardio-thoracic surgery
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Snippet This document presents a professional view of evidence-based recommendations around the issues of antiplatelet and anticoagulation management in cardiac...
Summary This document presents a professional view of evidence-based recommendations around the issues of antiplatelet and anticoagulation management in...
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SubjectTerms Anticoagulants - administration & dosage
Anticoagulants/administration & dosage/contraindications
Anticoagulation therapy
Antiplatelet therapy
Aprotinin - therapeutic use
Aspirin
Aspirin/contraindications
Biological and medical sciences
Cardiac Surgical Procedures
Cardiology. Vascular system
Cardiovascular & respiratory systems
Chirurgie
Contraindications
Evidence-Based Medicine
Guidelines
Heart Valve Prosthesis Implantation
Hemostasis, Surgical - methods
Hemostatics - therapeutic use
Human health sciences
Humans
Medical sciences
Monitoring, Intraoperative - instrumentation
Monitoring, Intraoperative - methods
Monitoring, Intraoperative/instrumentation/methods
Perioperative Care - methods
Platelet Aggregation Inhibitors - administration & dosage
Platelet Aggregation Inhibitors/administration & dosage/contraindications
Pneumology
Postoperative Hemorrhage - prevention & control
Sciences de la santé humaine
Surgery
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgery of the heart
Systèmes cardiovasculaire & respiratoire
Thoracic surgery
Ticlopidine - analogs & derivatives
Ticlopidine - therapeutic use
Ticlopidine/analogs & derivatives/therapeutic use
Tranexamic Acid - therapeutic use
Warfarin
Warfarin/contraindications
Title Guideline on antiplatelet and anticoagulation management in cardiac surgery
URI https://api.istex.fr/ark:/67375/HXZ-BGCR5P7D-R/fulltext.pdf
https://www.ncbi.nlm.nih.gov/pubmed/18375137
https://www.proquest.com/docview/69264349
http://orbi.ulg.ac.be/handle/2268/22534
http://kipublications.ki.se/Default.aspx?queryparsed=id:117370861
Volume 34
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