Effect of Lutein and Zeaxanthin on Macular Pigment and Visual Function in Patients with Early Age-related Macular Degeneration

• Published in: Ophthalmology (Rochester, Minn.) Vol. 119; no. 11; pp. 2290 - 2297
• Main Authors: Ma, Le, Yan, Shao-Fang, Huang, Yang-Mu, Lu, Xin-Rong, Qian, Fang, Pang, Hong-Lei, Xu, Xian-Rong, Zou, Zhi-Yong, Dong, Peng-Cheng, Xiao, Xin, Wang, Xun, Sun, Ting-Ting, Dou, Hong-Liang, Lin, Xiao-Ming
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.11.2012; Elsevier
• Subjects: Aged; Biological and medical sciences; Contrast Sensitivity; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Feeding Behavior; Female; Humans; Lutein - administration & dosage; Lutein - metabolism; Macular Degeneration - drug therapy; Macular Degeneration - metabolism; Male; Medical sciences; Middle Aged; Miscellaneous; Ophthalmology; Photic Stimulation; Prospective Studies; Retina - physiology; Retina - radiation effects; Retinal Pigments - metabolism; Retinopathies; Rhodopsin - metabolism; Surveys and Questionnaires; Visual Acuity - physiology; Xanthophylls - administration & dosage; Xanthophylls - metabolism; Zeaxanthins; Human; Macula; Zeaxanthin; Eye disease; Retinopathy; Xanthophyll; Pigments; Early; Age related macular degeneration; Ophthalmology; Carotenoid

To determine whether supplementation with lutein and zeaxanthin improves macular pigment and visual function in patients with early age-related macular degeneration (AMD). Randomized, double-masked, placebo-controlled trial. Participants with probable AMD who were 50 to 79 years of age were screened...