Hepatitis surface B antigen clearance induced by long-term tenofovir disoproxil fumarate monotherapy in chronic hepatitis B treatment: a meta-analysis and longitudinal modeling analysis - Jian, Weizhe; Yin, Yalin; Xue, Junsheng; Chen, Rong; Feng, Jingwen; Zeng, Jiayao; He, Ruoyi; Zhou, Tianyan (Virology journal, 2025)
Keywords: Antigens; Antiviral Agents - therapeutic use; CHB; chronic hepatitis B; DNA; Dosage and administration; Drug therapy; fumarates; HBsAg clearance; HBsAg seroconversion; Hepatitis B; hepatitis B antigens; Hepatitis B Surface Antigens - blood; Hepatitis B virus; Hepatitis B virus - drug effects; Hepatitis B virus - immunology; Hepatitis B, Chronic - drug therapy; Hepatitis B, Chronic - virology; Humans; Immune response; Longitudinal Studies; Medical research; Medicine, Experimental; meta-analysis; Model-based simulation; Physiological aspects; seroconversion; simulation models; systematic review; TDF; Tenofovir; Tenofovir - therapeutic use; therapeutics; Treatment Outcome; China; HBsAg clearance; Model-based simulation; CHB; HBsAg seroconversion; TDF