Is Intercellular Space Different Among Layers in Normal Esophageal Mucosa? An Electron Microscopic Study

• Published in: Digestive diseases and sciences Vol. 56; no. 12; pp. 3492 - 3497
• Main Authors: Park, Sanghoon, Chun, Hoon Jai, Jang, Jin Su, Keum, Bora, Seo, Yeon Seok, Kim, Yong Sik, Jeen, Yoon-Tae, Lee, Hong Sik, Um, Soon Ho, Kim, Chang Duck, Ryu, Ho Sang, Uhm, Chang-Sub, Lee, Sung Joon
• Format: Journal Article
• Language: English
• Published: Boston Springer US 01.12.2011; Springer; Springer Nature B.V
• Subjects: Adult; Biochemistry; Biological and medical sciences; Biopsy; Electron microscopy; Endoscopy, Gastrointestinal; Esophagus; Esophagus - pathology; Feeding. Feeding behavior; Female; Fundamental and applied biological sciences. Psychology; Gastroenterology; Gastroenterology. Liver. Pancreas. Abdomen; Gastroesophageal reflux; Gastroesophageal Reflux - diagnosis; Hepatology; Humans; Intestinal Mucosa - ultrastructure; Intracellular Space; Male; Medical sciences; Medicine; Medicine & Public Health; Microscopy, Electron, Transmission - methods; Middle Aged; Oncology; Original Article; Other diseases. Semiology; Reproducibility of Results; ROC Curve; Transplant Surgery; Vertebrates: anatomy and physiology, studies on body, several organs or systems; Transmission electron microscopy; Intercellular space; Inter-observer variation; Gastroesophageal reflux disease; Esophagus; Gastroesophageal reflux; Mucosa; Esophageal disease; Metabolic diseases; Electron microscopy; Anatomic pathology; Interindividual comparison; Gastroenterology; Digestive diseases

Background/Introduction Dilatation of intercellular space (IS) of esophageal epithelial cells is described as a sensitive early marker for epithelial damage by refluxate. Esophageal epithelia are morphologically subdivided into three layers according to the shape of the cells and nuclei. Meanwhile,...