Inherited epidermolysis bullosa and squamous cell carcinoma: a systematic review of 117 cases

• Published in: Orphanet journal of rare diseases Vol. 11; no. 1; p. 117
• Main Authors: Montaudié, H, Chiaverini, C, Sbidian, E, Charlesworth, A, Lacour, J-P
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 20.08.2016; BioMed Central
• Subjects: Carcinoma, Squamous Cell - metabolism; Carcinoma, Squamous Cell - pathology; Care and treatment; Diagnosis; Epidermolysis bullosa; Epidermolysis Bullosa - metabolism; Epidermolysis Bullosa - pathology; Genetic aspects; Humans; Review; Risk factors; Skin - metabolism; Skin - pathology; Squamous cell carcinoma; Systematic review; Chemotherapy; Cutaneous squamous cell carcinoma; Inherited epidermolysis bullosa; Radiotherapy; Target therapy

Inherited epidermolysis bullosa (EB) comprises a highly heterogeneous group of rare diseases characterized by exacerbated skin and/or mucosal fragility and blister formation after minor mechanical trauma. Level of cleavage in the skin, clinical features with immunofluorescence antigen mapping and/or...