Changes observed in radionuclide bone scans during and after teriparatide treatment for osteoporosis

• Published in: European journal of nuclear medicine and molecular imaging Vol. 39; no. 2; pp. 326 - 336
• Main Authors: Moore, Amelia E. B., Blake, Glen M., Taylor, Kathleen A., Ruff, Valerie A., Rana, Asad E., Wan, Xiaohai, Fogelman, Ignac
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer-Verlag 01.02.2012; Springer Nature B.V
• Subjects: Aged; Bone and Bones - diagnostic imaging; Bone and Bones - pathology; Bone Density; Bone Remodeling; Bone turnover; Bones; Cardiology; Drug therapy; Female; Humans; Imaging; Mandible; Medicine; Medicine & Public Health; Middle Aged; Nuclear Medicine; Oncology; Original; Original Article; Orthopedics; Osteogenesis; Osteoporosis; Osteoporosis - diagnosis; Osteoporosis - drug therapy; Osteoporosis, Postmenopausal - diagnosis; Osteoporosis, Postmenopausal - drug therapy; Parathyroid hormone; Pelvis; Post-menopause; Radioisotopes; Radiology; Radionuclide Imaging; Skeleton; Spine; Technetium Tc 99m Medronate - therapeutic use; Teriparatide - pharmacology; Time Factors; Whole Body Imaging - methods; Osteoporosis; Tc-MDP bone scan; Bone remodelling; Bone turnover markers; Teriparatide

Purpose Visual changes on radionuclide bone scans have been reported with teriparatide treatment. To assess this, serial studies were evaluated and quantified in ten postmenopausal women with osteoporosis treated with teriparatide (20 μg/day subcutaneous) who had 99m Tc-methylene diphosphonate (MDP)...