Cohesins and condensins orchestrate the 4D dynamics of yeast chromosomes during the cell cycle

• Published in: The EMBO journal Vol. 36; no. 18; pp. 2684 - 2697
• Main Authors: Lazar‐Stefanita, Luciana, Scolari, Vittore F, Mercy, Guillaume, Muller, Héloise, Guérin, Thomas M, Thierry, Agnès, Mozziconacci, Julien, Koszul, Romain
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 15.09.2017; EMBO Press; John Wiley and Sons Inc
• Subjects: Adenosine Triphosphatases - metabolism; Cell Cycle; Cell Cycle Proteins - metabolism; Chromosomal Proteins, Non-Histone - metabolism; chromosome segregation; Chromosomes, Fungal - metabolism; Cohesins; DNA-Binding Proteins - metabolism; EMBO06; EMBO09; EMBO13; Genetics; Hi‐C; Life Sciences; loop extrusion; Multiprotein Complexes - metabolism; replication profile; Saccharomyces cerevisiae - metabolism; Saccharomyces cerevisiae - physiology; SMC; Spatio-Temporal Analysis; SMC; Hi‐C; chromosome segregation; replication profile; loop extrusion; Chromatin; Repair & Recombination; Hi-C; SMC Subject Categories Cell Cycle; Epigenetics; Genomics & Functional Genomics; DNA Replication

Duplication and segregation of chromosomes involves dynamic reorganization of their internal structure by conserved architectural proteins, including the structural maintenance of chromosomes (SMC) complexes cohesin and condensin. Despite active investigation of the roles of these factors, a genome‐...