Satb2, modularity, and the evolvability of the vertebrate jaw

• Published in: Evolution & development Vol. 13; no. 6; pp. 549 - 564
• Main Authors: Fish, Jennifer L., Villmoare, Brian, Köbernick, Katja, Compagnucci, Claudia, Britanova, Olga, Tarabykin, Victor, Depew, Michael J.
• Format: Journal Article
• Language: English
• Published: United States Blackwell Publishing Ltd 01.11.2011
• Subjects: Animals; Biological Evolution; Chickens; Evolution & development; Fibroblast Growth Factor 8 - genetics; Fibroblast Growth Factor 8 - metabolism; Gene Dosage; Gene Expression Regulation, Developmental; Genetic Variation; Mandible - anatomy & histology; Mandible - embryology; Matrix Attachment Region Binding Proteins - genetics; Matrix Attachment Region Binding Proteins - metabolism; Mesoderm - embryology; Mice; Mouth; RNA, Messenger - biosynthesis; Transcription Factors - genetics; Transcription Factors - metabolism; Vertebrates; Xenopus; Zebrafish; Zebrafish Proteins - genetics; Zebrafish Proteins - metabolism

SUMMARY Modularity is a key mechanism bridging development and evolution and is fundamental to evolvability. Herein, we investigate modularity of the Vertebrate jaw with the aim of understanding mechanisms of its morphological evolution. Conservation of the basic structural bauplan of Vertebrate jaw...