Novel aspects of in vitro IL-2 or IFN-α enhanced NK cytotoxicity of healthy individuals based on NKG2D and CD161 NK cell receptor induction - KONJEVIC, G; MIRJACIC MARTINOVIC, K; VULETIC, A; RADENKOVIC, S (Biomedicine & pharmacotherapy, 2010)
Keywords: Adult; Biological and medical sciences; Cell Line, Tumor; Cytokines; Cytotoxicity, Immunologic - drug effects; Female; Humans; Interferon-alpha - pharmacology; Interleukin-2 - pharmacology; Internal Medicine; K562 Cells; Killer Cells, Natural - drug effects; Killer Cells, Natural - metabolism; Lymphocytes - drug effects; Lymphocytes - metabolism; Male; Medical Education; Medical sciences; Middle Aged; NK Cell Lectin-Like Receptor Subfamily B - biosynthesis; NK Cell Lectin-Like Receptor Subfamily B - blood; NK Cell Lectin-Like Receptor Subfamily B - genetics; NK Cell Lectin-Like Receptor Subfamily K - biosynthesis; NK Cell Lectin-Like Receptor Subfamily K - blood; NK Cell Lectin-Like Receptor Subfamily K - genetics; NK cell receptors; NK cells; Pharmacology. Drug treatments; Receptors, KIR2DL1 - antagonists & inhibitors; Receptors, KIR2DL1 - genetics; Receptors, KIR2DL3 - antagonists & inhibitors; Receptors, KIR2DL3 - genetics; Receptors, Natural Killer Cell - biosynthesis; Receptors, Natural Killer Cell - blood; Receptors, Natural Killer Cell - genetics; Up-Regulation - genetics; Cytokines; NK cells; NK cell receptors; Healthy subject; Induction; Alpha interferon; NKG2D receptor; Cytokine; Cytotoxicity; In vitro; Natural killer cell; Interleukin 2; T-Lymphocyte; Biological receptor