Cell surface engineering of Saccharomyces cerevisiae combined with membrane separation technology for xylitol production from rice straw hydrolysate

• Published in: Applied microbiology and biotechnology Vol. 100; no. 8; pp. 3477 - 3487
• Main Authors: Guirimand, Gregory, Sasaki, Kengo, Inokuma, Kentaro, Bamba, Takahiro, Hasunuma, Tomohisa, Kondo, Akihiko
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.04.2016; Springer Nature B.V
• Subjects: Analysis; Batch processes; beta-glucosidase; Biomass; Biomedical and Life Sciences; Bioprocessing; Biotechnological Products and Process Engineering; Biotechnology; Cell Engineering - methods; Cell surface; Cellular biology; Cellulose; Crop production; Culture Media - metabolism; Energy consumption; Engineering; Enzymes; Fermentation; Filtration - methods; Food industry; Fungi; Genetic recombination; Genomes; Glucosidase; Hydrolysates; Hydrolysis; Industrial applications; Industrial Microbiology - methods; Industrial production; Life Sciences; Lignocellulose; manufacturing; Membrane separation; Membranes; Microbial Genetics and Genomics; Microbiology; Nanofiltration; Nanotechnology; Oryza - chemistry; Oryza - microbiology; Pharmaceutical industry; Plant Stems - chemistry; Plant Stems - microbiology; Plasmids; Production costs; Reductases; Rice; Rice straw; Saccharomyces cerevisiae; Saccharomyces cerevisiae - genetics; Saccharomyces cerevisiae - metabolism; Separation; Straw; Studies; Sugar; value added; wastes; Xylanase; xylanases; Xylitol; Xylitol - biosynthesis; Xylose; Xylose - metabolism; Xylose reductase; Xylosidase; Yeast; β-Glucosidase; Xylitol; Hemicellulose; Yeast; Membrane filtration; Consolidated bioprocessing (CBP); Fermentation; Cell surface display

Xylitol, a value-added polyol deriving from D-xylose, is widely used in both the food and pharmaceutical industries. Despite extensive studies aiming to streamline the production of xylitol, the manufacturing cost of this product remains high while demand is constantly growing worldwide. Biotechnolo...