The Role of Immune Regulatory Cells in Nontraumatic Osteonecrosis of the Femoral Head: A Retrospective Clinical Study

• Published in: BioMed research international Vol. 2019; no. 2019; pp. 1 - 7
• Main Authors: Wang, Weiguo, Yue, Debo, Wang, Bailiang, Gao, Fuqiang, Ge, Juncheng, Ma, Jinhui, Sun, Wei
• Format: Journal Article
• Language: English
• Published: Cairo, Egypt Hindawi Publishing Corporation 2019; Hindawi; John Wiley & Sons, Inc
• Subjects: Adult; Alcohol; Apoptosis; Arthritis; Autoimmune diseases; B cells; B-1 cells; B-Lymphocytes - immunology; Biomedical materials; Bones; CD19 antigen; CD3 antigen; CD3 Complex - immunology; CD5 antigen; CD8 antigen; Cell number; Clinical trials; Comparative analysis; Cytokines; Etiology; Female; Femur; Femur Head - immunology; Femur Head Necrosis - immunology; Flow cytometry; Health aspects; Hospitals; Humans; Immune system; Immunity; Immunology; Immunoregulation; Infections; Joint surgery; Lymphocytes; Lymphocytes B; Lymphocytes T; Male; Necrosis; Osteonecrosis; Osteonecrosis - immunology; Osteoporosis; Pathogenesis; Peripheral blood; Retrospective Studies; Surgery; T cells; T-Lymphocytes - immunology; China; Japan

The immunologic factors have been implicated in the pathogenesis of osteonecrosis. We aimed to investigate the potential role of immune regulatory cells in the development of osteonecrosis of femoral head (ONFH). Sixty-seven patients diagnosed with ONFH and fifty-eight age-, height-, and weight-matc...