Elements of Immunoglobulin E Network Associate with Aortic valve Area in Patients with Acquired Aortic Stenosis

• Published in: Biomedicines Vol. 9; no. 1; p. 23
• Main Authors: Potaczek, Daniel P, Przytulska-Szczerbik, Aleksandra, Bazan-Socha, Stanisława, Jurczyszyn, Artur, Okumura, Ko, Nishiyama, Chiharu, Undas, Anetta, Wypasek, Ewa
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 31.12.2020; MDPI
• Subjects: (genetic) polymorphism; Allergens; aortic (valve) stenosis (AS; Aortic stenosis; Aortic valve; aortic valve area (AVA); Arteriosclerosis; Atherosclerosis; AVS; Cardiovascular disease; Communication; Coronary artery; FcԑRI α-subunit (FcԑRIα) gene (FCER1A); Gene polymorphism; Heart diseases; high-affinity IgE receptor (FcԑRI); Hypersensitivity; Immunoglobulin E; Immunoglobulins; Polymorphism; Serum levels; Stenosis; Poland; United States > US; Germany; immunoglobulin E (IgE); FcԑRI α-subunit (FcԑRIα) gene (FCER1A); (genetic) polymorphism; aortic valve area (AVA); aortic (valve) stenosis (AS; high-affinity IgE receptor (FcԑRI); AVS

Allergic mechanisms are likely involved in atherosclerosis and its clinical presentations, such as coronary artery disease (CAD). It has been previously reported that CAD severity associates with serum levels of immunoglobulin E (IgE), the molecule that, along with its high-affinity receptor (FcԑRI)...