High-Dose Vitamin C Tends to Kill Colorectal Cancer with High MALAT1 Expression

• Published in: Journal of oncology Vol. 2020; no. 2020; pp. 1 - 15
• Main Authors: Liang, Weijun, Deng, Kaifeng, Mo, Shanying, Li, Yu, Qin, Fengxian, Chen, Jifei, Huang, Yujie
• Format: Journal Article
• Language: English
• Published: Cairo, Egypt Hindawi Publishing Corporation 2020; Hindawi; John Wiley & Sons, Inc; Hindawi Limited
• Subjects: Animal experimentation; Apoptosis; Cancer therapies; Cell cycle; Cell growth; Colorectal cancer; Epigenetic inheritance; Experiments; Immunohistochemistry; Laboratory animals; Lung cancer; Mediation; Medical research; Medicine, Experimental; Metastasis; Vitamin C

Background. Vitamin C (Vc) deficiency is frequently observed in cancer sites and has been proposed to have an antitumor effect. However, the mechanism of Vc’s killing effect is not clear. Besides, epigenetic alterations exhibit significant effects on colorectal cancer (CRC). This study aimed to expl...