Investigation of the Mouse Infection Model for Echovirus 18 - Xiang, Lei; Zhai, Linlin; Ou, Guanyong; Zhao, Wei; Yang, Yang; Shen, Chenguang (Viruses, 2025)
Keywords: Animals; Antibodies; Aseptic meningitis; Brain - pathology; Brain - virology; Care and treatment; Children; Clinical isolates; Control; Diagnosis; Disease; Disease Models, Animal; Echovirus; echovirus 18; Echovirus Infections - pathology; Echovirus Infections - virology; Encephalitis; Encephalitis, Viral; Enterovirus B, Human - pathogenicity; Enteroviruses; Epidemics; Fatalities; Female; Genetic aspects; Health aspects; Identification and classification; IFNAR1 knockout mice; Infections; Measurement; Meningitis; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; mouse infection model; Muscle, Skeletal - pathology; Muscle, Skeletal - virology; Paralysis; pathogenesis; Pathogenicity; Receptor, Interferon alpha-beta - deficiency; Receptor, Interferon alpha-beta - genetics; Skeletal muscle; Testing; Transgenic animals; Vaccines; Viral antibodies; Viral infections; Viral Load; Viremia; Viruses; China; pathogenesis; IFNAR1 knockout mice; mouse infection model; viral load; echovirus 18