A No-Brainer! The Therapeutic Potential of TRIM Proteins in Viral and Central Nervous System Diseases - Hage, Adam; Janes, Mikhaila; Best, Sonja M. (Viruses, 2025)
Keywords: Animals; Apoptosis; Autophagy; Care and treatment; Central nervous system; Central nervous system diseases; Central Nervous System Diseases - drug therapy; Central Nervous System Diseases - therapy; CNS diseases; CRISPR; Disease; Drug development; E3 ubiquitin ligase; Enzymes; Genomes; Health aspects; Humans; Immunity (Disease); Immunity, Innate; Innate immunity; Ligases; Medical research; Medicine, Experimental; Nervous system; Neurodegenerative diseases; Neurosciences; Pathogens; Physiological aspects; PROTAC; protein degradation; Proteins; Review; Signal Transduction; tripartite motif (TRIM); Tripartite Motif Proteins - genetics; Tripartite Motif Proteins - metabolism; Tripartite Motif Proteins - therapeutic use; Ubiquitin; Ubiquitin-Protein Ligases - metabolism; Viral infections; Virus diseases; Virus Diseases - drug therapy; Viruses; West Nile virus; United States; disease therapeutic; innate immunity; PROTAC; CNS diseases; trim-away; tripartite motif (TRIM); E3 ubiquitin ligase; protein degradation; ubiquitin; virus infection