Distinct signaling of Drosophila chemoreceptors in olfactory sensory neurons

• Published in: Proceedings of the National Academy of Sciences - PNAS Vol. 113; no. 7; pp. E902 - E911
• Main Authors: Cao, Li-Hui, Jing, Bi-Yang, Yang, Dong, Zeng, Xiankun, Shen, Ying, Tu, Yuhai, Luo, Dong-Gen
• Format: Journal Article
• Language: English
• Published: United States National Academy of Sciences 16.02.2016; National Acad Sciences
• Series: PNAS Plus
• Subjects: Adaptation, Physiological; Animals; Biological Sciences; Calcium - metabolism; Chemosensory perception; Drosophila; Drosophila melanogaster - physiology; Insects; Neurons; Odorants; Odors; Olfactory Receptor Neurons - physiology; Patch-Clamp Techniques; PNAS Plus; Sensory Receptor Cells - metabolism; Signal Transduction; olfaction; sensory adaptation; OSN; Drosophila; chemoreceptor

In Drosophila, olfactory sensory neurons (OSNs) rely primarily on two types of chemoreceptors, odorant receptors (Ors) and ionotropic receptors (Irs), to convert odor stimuli into neural activity. The cellular signaling of these receptors in their native OSNs remains unclear because of the difficult...