A SARS–CoV-2 Spike Receptor Binding Motif Peptide Induces Anti-Spike Antibodies in Mice andIs Recognized by COVID-19 Patients

• Published in: Frontiers in immunology Vol. 13; p. 879946
• Main Authors: Pratesi, Federico, Errante, Fosca, Pacini, Lorenzo, Peña-Moreno, Irina Charlot, Quiceno, Sebastian, Carotenuto, Alfonso, Balam, Saidou, Konaté, Drissa, Diakité, Mahamadou M., Arévalo-Herrera, Myriam, Kajava, Andrey V., Rovero, Paolo, Corradin, Giampietro, Migliorini, Paola, Papini, Anna M., Herrera, Sócrates
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers 26.05.2022; Frontiers Media S.A
• Subjects: Animals; Antibodies, Viral; COVID-19; Emerging diseases; Human health and pathology; Humans; immunized animals; Immunology; Infectious diseases; Life Sciences; Mice; neutralizing Abs; Peptides; receptor binding motif; SARS-CoV-2; spike (S) protein; Spike Glycoprotein, Coronavirus; COVID-19; SARS-CoV-2; receptor binding motif; neutralizing Abs; spike (S) protein; immunized animals

The currently devastating pandemic of severe acute respiratory syndrome known as coronavirus disease 2019 or COVID-19 is caused by the coronavirus SARS-CoV-2. Both the virus and the disease have been extensively studied worldwide. A trimeric spike (S) protein expressed on the virus outer bilayer lea...