Transcriptomic Analysis of circRNAs in the Peripheral Blood of Nonarteritic Anterior Ischemic Optic Neuropathy

• Published in: BioMed research international Vol. 2020; no. 2020; pp. 1 - 13
• Main Authors: Han, Xiao, Wang, Xinling, Han, XIao, Zhang, Jiaming, Hou, Naifang, Xu, Haoyan, Xu, Xinling, Suo, Jinshan, Zheng, Yanwen
• Format: Journal Article
• Language: English
• Published: Cairo, Egypt Hindawi Publishing Corporation 2020; Hindawi; John Wiley & Sons, Inc
• Subjects: Age; Aged; Analysis; Bioinformatics; Blood; Cardiovascular disease; Cholesterol; Cluster analysis; Diabetes; Diabetic retinopathy; Edema; Encyclopedias; Enzymes; Female; Gene expression; Gene Expression Profiling; Gene Expression Regulation; Gene Ontology; Gene Regulatory Networks; Genes; Genomes; Health aspects; Hemoglobin; Humans; Hypertension; Ischemia; Lipoproteins; Male; Middle Aged; Molecular Sequence Annotation; Neurodegeneration; Next-generation sequencing; Optic neuropathy; Optic Neuropathy, Ischemic - blood; Optic Neuropathy, Ischemic - genetics; Oxidative metabolism; Oxidative stress; Pathogenesis; Peripheral blood; Polymerase chain reaction; Protein interaction; Protein Interaction Maps - genetics; Protein-protein interactions; Proteins; Quality control; RNA, Circular - genetics; RNA, Circular - metabolism; RNA, Messenger - genetics; RNA, Messenger - metabolism; Transcriptome - genetics; Variation; China; Beijing China; California; United States > US

The aim of the study is to explore the expression profile variation of circular RNAs (circRNAs) in the peripheral blood of subjects with nonarteritic anterior ischemic optic neuropathy (NAION) and without NAION, to analyze the differential expression results, and to predict the role of circRNAs in d...