Cardiac, skeletal, and smooth muscle mitochondrial respiration: are all mitochondria created equal?

• Published in: American journal of physiology. Heart and circulatory physiology Vol. 307; no. 3; pp. H346 - H352
• Main Authors: Park, Song-Young, Gifford, Jayson R., Andtbacka, Robert H. I., Trinity, Joel D., Hyngstrom, John R., Garten, Ryan S., Diakos, Nikolaos A., Ives, Stephen J., Dela, Flemming, Larsen, Steen, Drakos, Stavros, Richardson, Russell S.
• Format: Journal Article
• Language: English
• Published: United States American Physiological Society 01.08.2014
• Subjects: Cardiovascular system; Cell Respiration; Citrate (si)-Synthase - metabolism; Electron Transport Complex I - metabolism; Electron Transport Complex II - metabolism; Energetics and Metabolism; Energy Metabolism; Female; Humans; Male; Middle Aged; Mitochondria; Mitochondria, Heart - metabolism; Mitochondria, Muscle - metabolism; Muscle, Skeletal - metabolism; Muscle, Smooth - metabolism; Muscular system; Oxidative Phosphorylation; Phenotype; Phosphorylation; Respiration; Skeletal system; respiratory control ratio; feed arteries; oxidative phosphorylation capacity
• ISSN: 0363-6135; 1522-1539; 1522-1539
• DOI: 10.1152/ajpheart.00227.2014

Unlike cardiac and skeletal muscle, little is known about vascular smooth muscle mitochondrial respiration. Therefore, the present study examined mitochondrial respiratory rates in smooth muscle of healthy human feed arteries and compared with that of healthy cardiac and skeletal muscles. Cardiac, s...