Effect of Electroacupuncture Intervention on Expression of CGRP, SP, COX-1, and PGE2 of Dorsal Portion of the Cervical Spinal Cord in Rats with Neck-Incision Pain

• Published in: Evidence-based complementary and alternative medicine Vol. 2013; no. 2013; pp. 1 - 9
• Main Authors: Wang, Jun-ying, Chen, Shu-ping, Qiao, Li-na, Liu, Jun-ling, Zhang, Jian-liang, Gao, Yong-hui, Yang, Yong-sheng
• Format: Journal Article
• Language: English
• Published: Cairo, Egypt Hindawi Puplishing Corporation 01.01.2013; Hindawi Publishing Corporation; Hindawi Limited
• Subjects: Acupuncture; Analgesia; Analgesics; Calcitonin; Calcitonin gene-related peptide; Chinese medicine; Cyclooxygenase-1; Electroacupuncture; Enzyme-linked immunosorbent assay; Gene expression; Immunofluorescence; Laboratory animals; Neck; Neurokinin; Neurokinin NK1 receptors; Neurosciences; Pain; Pain perception; Prostaglandin E2; Rats; Rodents; Spinal cord; Stimulation; Substance P; Surgery; Thyroid; Thyroid gland; China

The present study was aimed to determine if cervicospinal substance P (SP) and its neurokinin-1 receptor (NK-1R), calcitonin gene-related peptide (CGRP), cyclooxygenase-1 (COX-1), and prostaglandin E2 (PGE2) were involved in electroacupuncture (EA) analgesia in neck-incision pain rats. EA interventi...