MMP9 inhibition increases autophagic flux in chronic heart failure - Nandi, Shyam S.; Katsurada, Kenichi; Sharma, Neeru M.; Anderson, Daniel R.; Mahata, Sushil K.; Patel, Kaushik P. (American journal of physiology. Heart and circulatory physiology, 2020)
Keywords: Ablation; Animals; Autophagy; Autophagy - drug effects; Benzofurans - pharmacology; Blood pressure; Cardiomyocytes; Cell Line; Congestive heart failure; Coronary artery; CRISPR; Diastolic pressure; Disease Models, Animal; Fibroblasts; Fibroblasts - drug effects; Fibroblasts - enzymology; Fibroblasts - pathology; Fibrosis; Fluctuations; Flux; Gelatinase B; Heart failure; Heart Failure - drug therapy; Heart Failure - enzymology; Heart Failure - pathology; Heart Failure - physiopathology; Inhibition; Inhibitors; Ischemia; Male; Matrix metalloproteinase; Matrix Metalloproteinase 9 - genetics; Matrix Metalloproteinase 9 - metabolism; Matrix Metalloproteinase Inhibitors - pharmacology; Metalloproteinase; Mice; Myocardial infarction; Myocardium; Myocytes, Cardiac - drug effects; Myocytes, Cardiac - enzymology; Myocytes, Cardiac - pathology; Phagocytosis; Pharmacology; Rats, Sprague-Dawley; Rodents; Signal Transduction; Surgery; Ventricle; Ventricular Function, Left - drug effects; Ventricular Remodeling - drug effects; autophagic flux; chronic heart failure; matrix metalloprotease 9; myocardial infarction