Ultrasound carotid plaque features, cardiovascular disease risk factors and events: The Multi-Ethnic Study of Atherosclerosis
It is not known if ultrasound carotid plaque features are associated with cardiovascular disease (CVD) risk factors or if they predict future CVD events. We measured total carotid plaque area (TPA) and grayscale plaque features (grayscale median, black areas, and discrete white areas) by B-mode caro...
Saved in:
| Published in | Atherosclerosis Vol. 276; pp. 195 - 202 |
|---|---|
| Main Authors | , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Ireland
Elsevier B.V
01.09.2018
|
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | It is not known if ultrasound carotid plaque features are associated with cardiovascular disease (CVD) risk factors or if they predict future CVD events.
We measured total carotid plaque area (TPA) and grayscale plaque features (grayscale median, black areas, and discrete white areas) by B-mode carotid ultrasound among 2205 participants who participated in the first (baseline) visit of the Multi-Ethnic Study of Atherosclerosis. Multivariable linear regression was used to examine relationships between ultrasound plaque features and CVD risk factors at baseline. Cox proportional hazards models were used to assess if TPA, grayscale features, and carotid plaque score (number of arterial segments with a plaque) could predict incident coronary heart disease and cerebrovascular disease events over a mean follow-up of 13.3 years.
Participants were mean (standard deviation [SD]) 65.4 (9.6) years, 49% male, 39% White, 11% Chinese, 28% Black, and 22% Hispanic. Mean TPA 27.7 (24.7) mm2, but no grayscale plaque features, was associated with CVD risk factors. In fully adjusted models, TPA but no grayscale features predicted incident coronary heart disease (CHD) events (HR 1.23; 95%CI 1.11–1.36; p<0.001), however, C-statistics for CHD were similar to carotid plaque score but less than for coronary artery calcium (CAC) scoring. Neither TPA nor grayscale features independently predicted cerebrovascular events.
In middle-aged adults free of known cardiovascular disease, TPA but not grayscale plaque features was associated with CVD risk factors and predicted incident CHD events. For CHD, prediction indices for TPA were similar to carotid plaque score but less than for CAC.
In middle-aged individuals free of known cardiovascular disease;•Total plaque area was associated with CHD risk factors and predicted incident CHD events.•Grayscale carotid plaque features did not predict incident CHD events.•For CHD, predictive characteristics of TPA were similar to carotid plaque score, but less than CAC score. |
|---|---|
| AbstractList | It is not known if ultrasound carotid plaque features are associated with cardiovascular disease (CVD) risk factors or if they predict future CVD events.BACKGROUND AND AIMSIt is not known if ultrasound carotid plaque features are associated with cardiovascular disease (CVD) risk factors or if they predict future CVD events.We measured total carotid plaque area (TPA) and grayscale plaque features (grayscale median, black areas, and discrete white areas) by B-mode carotid ultrasound among 2205 participants who participated in the first (baseline) visit of the Multi-Ethnic Study of Atherosclerosis. Multivariable linear regression was used to examine relationships between ultrasound plaque features and CVD risk factors at baseline. Cox proportional hazards models were used to assess if TPA, grayscale features, and carotid plaque score (number of arterial segments with a plaque) could predict incident coronary heart disease and cerebrovascular disease events over a mean follow-up of 13.3 years.METHODSWe measured total carotid plaque area (TPA) and grayscale plaque features (grayscale median, black areas, and discrete white areas) by B-mode carotid ultrasound among 2205 participants who participated in the first (baseline) visit of the Multi-Ethnic Study of Atherosclerosis. Multivariable linear regression was used to examine relationships between ultrasound plaque features and CVD risk factors at baseline. Cox proportional hazards models were used to assess if TPA, grayscale features, and carotid plaque score (number of arterial segments with a plaque) could predict incident coronary heart disease and cerebrovascular disease events over a mean follow-up of 13.3 years.Participants were mean (standard deviation [SD]) 65.4 (9.6) years, 49% male, 39% White, 11% Chinese, 28% Black, and 22% Hispanic. Mean TPA 27.7 (24.7) mm2, but no grayscale plaque features, was associated with CVD risk factors. In fully adjusted models, TPA but no grayscale features predicted incident coronary heart disease (CHD) events (HR 1.23; 95%CI 1.11-1.36; p<0.001), however, C-statistics for CHD were similar to carotid plaque score but less than for coronary artery calcium (CAC) scoring. Neither TPA nor grayscale features independently predicted cerebrovascular events.RESULTSParticipants were mean (standard deviation [SD]) 65.4 (9.6) years, 49% male, 39% White, 11% Chinese, 28% Black, and 22% Hispanic. Mean TPA 27.7 (24.7) mm2, but no grayscale plaque features, was associated with CVD risk factors. In fully adjusted models, TPA but no grayscale features predicted incident coronary heart disease (CHD) events (HR 1.23; 95%CI 1.11-1.36; p<0.001), however, C-statistics for CHD were similar to carotid plaque score but less than for coronary artery calcium (CAC) scoring. Neither TPA nor grayscale features independently predicted cerebrovascular events.In middle-aged adults free of known cardiovascular disease, TPA but not grayscale plaque features was associated with CVD risk factors and predicted incident CHD events. For CHD, prediction indices for TPA were similar to carotid plaque score but less than for CAC.CONCLUSIONSIn middle-aged adults free of known cardiovascular disease, TPA but not grayscale plaque features was associated with CVD risk factors and predicted incident CHD events. For CHD, prediction indices for TPA were similar to carotid plaque score but less than for CAC. It is not known if ultrasound carotid plaque features are associated with cardiovascular disease (CVD) risk factors or if they predict future CVD events. We measured total carotid plaque area (TPA) and grayscale plaque features (grayscale median, black areas, and discrete white areas) by B-mode carotid ultrasound among 2205 participants who participated in the first (baseline) visit of the Multi-Ethnic Study of Atherosclerosis. Multivariable linear regression was used to examine relationships between ultrasound plaque features and CVD risk factors at baseline. Cox proportional hazards models were used to assess if TPA, grayscale features, and carotid plaque score (number of arterial segments with a plaque) could predict incident coronary heart disease and cerebrovascular disease events over a mean follow-up of 13.3 years. Participants were mean (standard deviation [SD]) 65.4 (9.6) years, 49% male, 39% White, 11% Chinese, 28% Black, and 22% Hispanic. Mean TPA 27.7 (24.7) mm , but no grayscale plaque features, was associated with CVD risk factors. In fully adjusted models, TPA but no grayscale features predicted incident coronary heart disease (CHD) events (HR 1.23; 95%CI 1.11-1.36; p<0.001), however, C-statistics for CHD were similar to carotid plaque score but less than for coronary artery calcium (CAC) scoring. Neither TPA nor grayscale features independently predicted cerebrovascular events. In middle-aged adults free of known cardiovascular disease, TPA but not grayscale plaque features was associated with CVD risk factors and predicted incident CHD events. For CHD, prediction indices for TPA were similar to carotid plaque score but less than for CAC. It is not known if ultrasound carotid plaque features are associated with cardiovascular disease (CVD) risk factors or if they predict future CVD events. We measured total carotid plaque area (TPA) and grayscale plaque features (grayscale median, black areas, and discrete white areas) by B-mode carotid ultrasound among 2205 participants who participated in the first (baseline) visit of the Multi-Ethnic Study of Atherosclerosis. Multivariable linear regression was used to examine relationships between ultrasound plaque features and CVD risk factors at baseline. Cox proportional hazards models were used to assess if TPA, grayscale features, and carotid plaque score (number of arterial segments with a plaque) could predict incident coronary heart disease and cerebrovascular disease events over a mean follow-up of 13.3 years. Participants were mean (standard deviation [SD]) 65.4 (9.6) years, 49% male, 39% White, 11% Chinese, 28% Black, and 22% Hispanic. Mean TPA 27.7 (24.7) mm2, but no grayscale plaque features, was associated with CVD risk factors. In fully adjusted models, TPA but no grayscale features predicted incident coronary heart disease (CHD) events (HR 1.23; 95%CI 1.11–1.36; p<0.001), however, C-statistics for CHD were similar to carotid plaque score but less than for coronary artery calcium (CAC) scoring. Neither TPA nor grayscale features independently predicted cerebrovascular events. In middle-aged adults free of known cardiovascular disease, TPA but not grayscale plaque features was associated with CVD risk factors and predicted incident CHD events. For CHD, prediction indices for TPA were similar to carotid plaque score but less than for CAC. In middle-aged individuals free of known cardiovascular disease;•Total plaque area was associated with CHD risk factors and predicted incident CHD events.•Grayscale carotid plaque features did not predict incident CHD events.•For CHD, predictive characteristics of TPA were similar to carotid plaque score, but less than CAC score. |
| Author | McClelland, Robyn L. Gepner, Adam D. Stein, James H. Mitchell, Carol Korcarz, Claudia E. Tracy, Russell Gassett, Amanda J. Ma, Nanxun Kaufman, Joel D. Post, Wendy |
| AuthorAffiliation | e Departments of Pathology & Laboratory Medicine, Biochemistry Larner College of Medicine, University of Vermont, 360 South Park Drive, Colchester, VT, 05446, USA c Departments of Environmental & Occupational Health Sciences, Medicine, and Epidemiology, University of Washington, 4225 Roosevelt Way NE, Seattle, WA, 98105, USA d Division of Cardiology, Department of Medicine, Johns Hopkins University, 600 N. Wolfe Street, Baltimore MD, 21287, USA f Department of Environmental & Occupational Health Sciences, University of Washington, 1959 NE Pacific Street, Seattle, WA, 98195, USA a Department of Medicine, Division of Cardiovascular Medicine, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, Madison WI, 53792, USA b William S. Middleton Memorial Veterans Hospital, 2500 Overlook Terrace, Madison, WI 53705, USA g Department of Biostatistics, University of Washington, 6200 NE 74 th Street, Seattle, WA, 98115, USA |
| AuthorAffiliation_xml | – name: e Departments of Pathology & Laboratory Medicine, Biochemistry Larner College of Medicine, University of Vermont, 360 South Park Drive, Colchester, VT, 05446, USA – name: c Departments of Environmental & Occupational Health Sciences, Medicine, and Epidemiology, University of Washington, 4225 Roosevelt Way NE, Seattle, WA, 98105, USA – name: a Department of Medicine, Division of Cardiovascular Medicine, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, Madison WI, 53792, USA – name: f Department of Environmental & Occupational Health Sciences, University of Washington, 1959 NE Pacific Street, Seattle, WA, 98195, USA – name: b William S. Middleton Memorial Veterans Hospital, 2500 Overlook Terrace, Madison, WI 53705, USA – name: d Division of Cardiology, Department of Medicine, Johns Hopkins University, 600 N. Wolfe Street, Baltimore MD, 21287, USA – name: g Department of Biostatistics, University of Washington, 6200 NE 74 th Street, Seattle, WA, 98115, USA |
| Author_xml | – sequence: 1 givenname: Carol surname: Mitchell fullname: Mitchell, Carol email: ccm@medicine.wisc.edu organization: Department of Medicine, Division of Cardiovascular Medicine, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, Madison, WI, 53792, USA – sequence: 2 givenname: Claudia E. surname: Korcarz fullname: Korcarz, Claudia E. organization: Department of Medicine, Division of Cardiovascular Medicine, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, Madison, WI, 53792, USA – sequence: 3 givenname: Adam D. surname: Gepner fullname: Gepner, Adam D. organization: Department of Medicine, Division of Cardiovascular Medicine, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, Madison, WI, 53792, USA – sequence: 4 givenname: Joel D. surname: Kaufman fullname: Kaufman, Joel D. organization: Departments of Environmental & Occupational Health Sciences, Medicine, and Epidemiology, University of Washington, 4225 Roosevelt Way NE, Seattle, WA, 98105, USA – sequence: 5 givenname: Wendy surname: Post fullname: Post, Wendy organization: Division of Cardiology, Department of Medicine, Johns Hopkins University, 600 N. Wolfe Street, Baltimore, MD, 21287, USA – sequence: 6 givenname: Russell surname: Tracy fullname: Tracy, Russell organization: Departments of Pathology & Laboratory Medicine, Biochemistry Larner College of Medicine, University of Vermont, 360 South Park Drive, Colchester, VT, 05446, USA – sequence: 7 givenname: Amanda J. surname: Gassett fullname: Gassett, Amanda J. organization: Department of Environmental & Occupational Health Sciences, University of Washington, 1959 NE Pacific Street, Seattle, WA, 98195, USA – sequence: 8 givenname: Nanxun surname: Ma fullname: Ma, Nanxun organization: Department of Biostatistics, University of Washington, 6200 NE, 74thStreet, Seattle, WA, 98115, USA – sequence: 9 givenname: Robyn L. surname: McClelland fullname: McClelland, Robyn L. organization: Department of Biostatistics, University of Washington, 6200 NE, 74thStreet, Seattle, WA, 98115, USA – sequence: 10 givenname: James H. surname: Stein fullname: Stein, James H. organization: Department of Medicine, Division of Cardiovascular Medicine, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, Madison, WI, 53792, USA |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/29970256$$D View this record in MEDLINE/PubMed |
| BookMark | eNqNUcFu1DAQtVAR3bb8AvIFiQMJduI4MRKVqqoUpCIObc_WxB6zXrLxYjsr9cC_k2VLRXvqZeYwb957M--IHIxhRELeclZyxuWHVQl5iTEkM-yqT2XFeFcyWTLWvCAL3rWq4KITB2TBWMULxRt2SI5SWjHGRMu7V-SwUqplVSMX5PftkCOkMI2WGoghe0s3A_yakDqEPEVM73cD68MWkpkGiNT6hJCQRp9-Ugcmh5gozAS4xTGnj_RmifTbNGRfXOTl6A29zpO9o8HRs8feT8hLB0PC1_f9mNx-vrg5_1Jcfb_8en52VRihVC4kuLruOUIterC24h1Hhz3Wosaat03DHW9MDx2gkBZbXitwTkKvVGMsZ_UxOd3zbqZ-jdbMNiMMehP9GuKdDuD148nol_pH2OpW1FIJMRO8uyeIYf5Nynrtk8FhgBHDlHTFpKhEJf9qfdpDzXxiiugeZDjTuwj1Sj-JUO8i1EzqOcJ5_83_Xh-2_2U2Ay73AJw_tvUYdTIeR4PWRzRZ2-CfKfUHzii-Yw |
| CitedBy_id | crossref_primary_10_1016_j_ijcard_2019_06_038 crossref_primary_10_1016_j_atherosclerosis_2020_09_015 crossref_primary_10_1186_s12872_022_02942_w crossref_primary_10_3389_fcvm_2023_1215449 crossref_primary_10_1186_s41983_021_00294_4 crossref_primary_10_1159_000536426 crossref_primary_10_1161_JAHA_123_032659 crossref_primary_10_1016_j_echo_2019_06_007 crossref_primary_10_1016_j_bspc_2024_106035 crossref_primary_10_1186_s12872_023_03580_6 crossref_primary_10_17816_DD71633 crossref_primary_10_3233_ADR_200180 crossref_primary_10_1016_j_clinbiochem_2021_04_005 crossref_primary_10_3389_fcvm_2022_793755 crossref_primary_10_1016_j_ypmed_2021_106819 crossref_primary_10_1161_JAHA_118_010875 crossref_primary_10_3390_diagnostics12030722 crossref_primary_10_1177_0003319719862681 crossref_primary_10_3389_fcvm_2022_903390 crossref_primary_10_3389_fcvm_2021_706490 crossref_primary_10_1177_20503121241261840 crossref_primary_10_1111_jch_14602 crossref_primary_10_3389_fpsyt_2024_1326745 crossref_primary_10_3390_ijms23031332 crossref_primary_10_3390_brainsci13010143 crossref_primary_10_1007_s11886_020_01375_1 crossref_primary_10_1177_1358863X19867762 crossref_primary_10_3390_life14030333 crossref_primary_10_1038_s41371_021_00640_2 crossref_primary_10_1155_2022_2014349 crossref_primary_10_1038_s41430_020_00756_7 crossref_primary_10_12998_wjcc_v9_i28_8366 crossref_primary_10_4155_fmc_2018_0463 crossref_primary_10_1002_art_40925 crossref_primary_10_18087_cardio_2021_6_n1536 crossref_primary_10_3390_app12199751 crossref_primary_10_3390_diagnostics11122257 crossref_primary_10_1038_s41440_020_0432_2 crossref_primary_10_3390_gucdd1030014 crossref_primary_10_2478_arsm_2020_0022 crossref_primary_10_1177_8756479320929017 crossref_primary_10_25259_IJCDW_7_2024 crossref_primary_10_3390_jcm8111897 crossref_primary_10_1016_S1474_4422_19_30035_3 crossref_primary_10_3390_jpm11090897 crossref_primary_10_1016_j_atherosclerosis_2018_07_011 |
| Cites_doi | 10.1148/radiol.2341040439 10.1161/01.CIR.0000018650.58984.75 10.1016/j.jacc.2009.11.075 10.1016/j.nic.2015.09.006 10.1161/01.cir.0000437741.48606.98 10.1161/01.STR.0000042207.16156.B9 10.1016/S1078-5884(96)80172-9 10.1016/j.jvs.2012.09.045 10.1001/archinte.168.12.1333 10.1161/STROKEAHA.114.005752 10.1161/STROKEAHA.114.005669 10.1111/j.1751-7141.2008.00021.x 10.1067/mva.2002.122888 10.1016/j.atherosclerosis.2007.03.029 10.1161/ATVBAHA.115.305452 10.1161/01.ATV.15.9.1512 10.1093/aje/kwf113 10.1016/j.jvs.2016.03.423 10.1161/CIR.0000000000000485 10.1016/j.jvs.2010.02.265 10.1097/00004872-199715010-00004 10.1161/STROKEAHA.107.498634 10.1161/01.STR.0000157599.10026.ad 10.1016/j.ultrasmedbio.2016.08.011 10.1161/CIRCIMAGING.110.959403 10.1016/j.ejvs.2007.12.011 10.1016/j.jvs.2010.07.021 10.1371/journal.pone.0142138 10.1016/j.jacc.2015.08.035 10.1016/j.ejvs.2014.05.015 10.4250/jcu.2016.24.2.91 10.1161/01.STR.0000116103.19029.DB 10.1159/000330654 10.1161/CIRCIMAGING.114.002262 10.1161/STROKEAHA.106.480830 10.1161/STROKEAHA.107.487264 |
| ContentType | Journal Article |
| Copyright | 2018 Elsevier B.V. Copyright © 2018 Elsevier B.V. All rights reserved. |
| Copyright_xml | – notice: 2018 Elsevier B.V. – notice: Copyright © 2018 Elsevier B.V. All rights reserved. |
| DBID | CGR CUY CVF ECM EIF NPM AAYXX CITATION 7X8 5PM |
| DOI | 10.1016/j.atherosclerosis.2018.06.005 |
| DatabaseName | Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed CrossRef MEDLINE - Academic PubMed Central (Full Participant titles) |
| DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) CrossRef MEDLINE - Academic |
| DatabaseTitleList | MEDLINE - Academic MEDLINE |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine |
| EISSN | 1879-1484 |
| EndPage | 202 |
| ExternalDocumentID | 10_1016_j_atherosclerosis_2018_06_005 29970256 S0021915018303125 |
| Genre | Research Support, U.S. Gov't, Non-P.H.S Multicenter Study Comparative Study Journal Article Observational Study Research Support, N.I.H., Extramural |
| GeographicLocations | United States |
| GeographicLocations_xml | – name: United States |
| GrantInformation_xml | – fundername: NHLBI NIH HHS grantid: N01HC95169 – fundername: NHLBI NIH HHS grantid: N01 HC095160 – fundername: NHLBI NIH HHS grantid: N01HC95161 – fundername: NHLBI NIH HHS grantid: N01 HC095168 – fundername: NHLBI NIH HHS grantid: N01HC95164 – fundername: NHLBI NIH HHS grantid: N01 HC095165 – fundername: NHLBI NIH HHS grantid: N01 HC095162 – fundername: NHLBI NIH HHS grantid: N01HC95167 – fundername: NHLBI NIH HHS grantid: N01HC95159 – fundername: NHLBI NIH HHS grantid: N01HC95163 |
| GroupedDBID | --- --K --M .1- .55 .FO .GJ .~1 0R~ 0SF 1B1 1P~ 1RT 1~. 1~5 23N 3O- 4.4 457 4G. 53G 5GY 5RE 5VS 7-5 71M 8P~ 9JM AABNK AACTN AAEDT AAEDW AAIAV AAIKJ AAKOC AALRI AAOAW AAQFI AAXUO ABBQC ABFNM ABJNI ABLJU ABLVK ABMAC ABMZM ABOCM ABXDB ABYKQ ACDAQ ACGFS ACIUM ACRLP ADBBV ADEZE AEBSH AEKER AENEX AEVXI AEXQZ AFCTW AFFNX AFKWA AFRHN AFTJW AFXIZ AGHFR AGUBO AGYEJ AHHHB AHPSJ AIEXJ AIKHN AITUG AJBFU AJOXV AJRQY AJUYK ALMA_UNASSIGNED_HOLDINGS AMFUW AMRAJ ANZVX ASPBG AVWKF AXJTR AZFZN BKOJK BLXMC BNPGV CS3 EBS EFJIC EFLBG EJD EO8 EO9 EP2 EP3 F5P FDB FEDTE FGOYB FIRID FNPLU FYGXN G-2 G-Q GBLVA HEB HMK HMO HVGLF HZ~ IHE J1W J5H K-O KOM L7B LCYCR M27 M41 MO0 N9A NCXOZ O-L O9- OAUVE OA~ OK1 OL0 OZT P-8 P-9 P2P PC. Q38 R2- RIG ROL RPZ SAE SCC SDF SDG SDP SEL SES SEW SPCBC SSH SSZ T5K WUQ X7M Z5R ZA5 ZGI ZXP ~G- ~KM AAXKI AFJKZ AKRWK CGR CUY CVF ECM EIF NPM AAYXX CITATION 7X8 5PM |
| ID | FETCH-LOGICAL-c499t-6af33b1ea34badd2181efebe343e317551f15cba8ae46de7139aff6ab995cd103 |
| IEDL.DBID | AIKHN |
| ISSN | 0021-9150 1879-1484 |
| IngestDate | Tue Sep 17 21:19:56 EDT 2024 Wed Aug 07 11:41:50 EDT 2024 Thu Sep 26 18:21:37 EDT 2024 Tue Oct 15 08:56:50 EDT 2024 Fri Feb 23 02:28:34 EST 2024 |
| IsDoiOpenAccess | false |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Keywords | CRP GSM MESA BAB CAC TPA Carotid ultrasound Echogenicity ICC Cardiovascular disease TIA DWA CHD Plaque |
| Language | English |
| License | Copyright © 2018 Elsevier B.V. All rights reserved. |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c499t-6af33b1ea34badd2181efebe343e317551f15cba8ae46de7139aff6ab995cd103 |
| Notes | ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 ObjectType-Undefined-3 Author Contributions Carol Mitchell and James Stein developed and designed the study to measure grayscale carotid plaque features. Claudia Korcarz performed data retrieval and developed the database for recording and archiving grayscale carotid plaque measurements. Robyn McClelland developed the statistical methods used in this study and helped interpret the results. Amanda Gassett and Nanxun Ma performed data/statistical analyses. Adam Gepner assisted with image analysis and data interpretation. Joel Kaufman, Wendy Post and Russell Tracy were responsible for interpreting MESA clinical reports and measures in preparation for statistical analyses. All authors assisted with writing of the manuscript. |
| OpenAccessLink | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7436944 |
| PMID | 29970256 |
| PQID | 2064242610 |
| PQPubID | 23479 |
| PageCount | 8 |
| ParticipantIDs | pubmedcentral_primary_oai_pubmedcentral_nih_gov_7436944 proquest_miscellaneous_2064242610 crossref_primary_10_1016_j_atherosclerosis_2018_06_005 pubmed_primary_29970256 elsevier_sciencedirect_doi_10_1016_j_atherosclerosis_2018_06_005 |
| PublicationCentury | 2000 |
| PublicationDate | 2018-09-01 |
| PublicationDateYYYYMMDD | 2018-09-01 |
| PublicationDate_xml | – month: 09 year: 2018 text: 2018-09-01 day: 01 |
| PublicationDecade | 2010 |
| PublicationPlace | Ireland |
| PublicationPlace_xml | – name: Ireland |
| PublicationTitle | Atherosclerosis |
| PublicationTitleAlternate | Atherosclerosis |
| PublicationYear | 2018 |
| Publisher | Elsevier B.V |
| Publisher_xml | – name: Elsevier B.V |
| References | Stary, Chandler, Dinsmore, Fuster, Glagov (bib16) 1995; 15 Barnett, Spence, Manuck, Jennings (bib34) 1997; 15 Ostling, Hedblad, Berglund, Concalves (bib23) 2007; 38 Mitchell, Stein, Cook, Salamat, Wang (bib17) 2017; 43 Jain, McClelland, Polak, Shea, Burke (bib27) 2011; 4 Hollander, Bots, Del Sol, Koudstaal, Witteman (bib8) 2002; 105 Gepner, Young, Delaney, Tattersall, Blaha (bib3) 2015; 8 van Engelen, Wannarong, Parraga, Niessen, Fenster (bib39) 2014; 45 Virmani, Ladich, Burke, Kolodgie (bib15) 2006; 59 Nambi, Chambless, Folsom, He, Hu (bib7) 2010; 55 Spence, Hegele (bib40) 2004; 35 Tattersall, Gassett, Korcarz, Gepner, Kaufman (bib26) 2014; 45 Salem, Bown, Sayers, West, Moore (bib14) 2014; 48 Stein, Korcarz, Post (bib4) 2009; 12 Lal, Hobson, Pappas, Kubicka, Hameed (bib35) 2002; 35 Spence, Eliasziw, DiCicco, Hackam, Galil (bib9) 2002; 33 Ruiz-Ares, Fuentes, Martinez-Sanchez, Martinez-Martinez (bib19) 2011; 32 Gepner, Young, Delaney, Budoff, Polak (bib2) 2017; 6 Goff, Lloyd-Jones, Bennett, Coady, D'Agostino (bib5) 2014; 129 Doonan, Gorgui, Veinot, Lai, Kyriacou (bib33) 2016; 64 Folsom, Kronmal, Detrano, O'Leary, Bild (bib32) 2008; 168 Johnsen, Mathiesen, Joakimsen, Stensland, Wilsgaard (bib11) 2007; 38 El-Barghouty, Levine, Ladva, Flanagan, Nicolaides (bib36) 1996; 11 Lind, Andersson, Rönn, Gustavsson (bib24) 2007; 195 McClelland, Jorgensen, Budoff, Glaha, Post (bib10) 2015; 66 Sztajzel, Momjian, Momjian-Mayor, Murith, Djebaili (bib20) 2005; 36 Tattersall, Guo, Korcarz, Gepner, Kaufman (bib31) 2015; 35 Carr, Nelson, Wong, McNitt-Gray, Arad (bib37) 2005; 234 Nicolaides, Kakkos, Kyriacou, Griffin, Sabetai (bib13) 2010; 52 Griffin, Kyriacou, Pattichis, Bond, Kakkos (bib21) 2010; 52 Benjamin, Blaha, Chiuve, Cushman, Das (bib1) 2017; 135 Goff, Lloyd-Jones, Coady, D'Agostino, Gibbons (bib6) 2014; 129 Bild, Bluemke, Burke, Detrano, Diez Roux (bib25) 2002; 156 Kakkos, Griffin, Nicolaides, Kyriacou, Sabetai (bib18) 2013; 57 Gepner, Colangelo, Reilly, Korcarz, Kaufman (bib29) 2015; 10 Tattersall, Guo, Korcarz, Gepner, Kaufman (bib30) 2015; 35 Park (bib12) 2016; 24 Kadoglou, Gerasimidis, Moumtzouoglou, Kapelouzou, Sailer (bib22) 2008; 35 Wasserman, Sharrett, Lai, Gomes, Folsom (bib28) 2008; 39 Spence, Parraga (bib38) 2016; 26 30031592 - Atherosclerosis. 2018 Sep;276:166-167. doi: 10.1016/j.atherosclerosis.2018.07.011 Gepner (10.1016/j.atherosclerosis.2018.06.005_bib2) 2017; 6 Park (10.1016/j.atherosclerosis.2018.06.005_bib12) 2016; 24 Hollander (10.1016/j.atherosclerosis.2018.06.005_bib8) 2002; 105 Spence (10.1016/j.atherosclerosis.2018.06.005_bib38) 2016; 26 Kakkos (10.1016/j.atherosclerosis.2018.06.005_bib18) 2013; 57 Jain (10.1016/j.atherosclerosis.2018.06.005_bib27) 2011; 4 Nambi (10.1016/j.atherosclerosis.2018.06.005_bib7) 2010; 55 Stary (10.1016/j.atherosclerosis.2018.06.005_bib16) 1995; 15 Benjamin (10.1016/j.atherosclerosis.2018.06.005_bib1) 2017; 135 McClelland (10.1016/j.atherosclerosis.2018.06.005_bib10) 2015; 66 Griffin (10.1016/j.atherosclerosis.2018.06.005_bib21) 2010; 52 Wasserman (10.1016/j.atherosclerosis.2018.06.005_bib28) 2008; 39 Stein (10.1016/j.atherosclerosis.2018.06.005_bib4) 2009; 12 Kadoglou (10.1016/j.atherosclerosis.2018.06.005_bib22) 2008; 35 Tattersall (10.1016/j.atherosclerosis.2018.06.005_bib31) 2015; 35 El-Barghouty (10.1016/j.atherosclerosis.2018.06.005_bib36) 1996; 11 Spence (10.1016/j.atherosclerosis.2018.06.005_bib40) 2004; 35 Sztajzel (10.1016/j.atherosclerosis.2018.06.005_bib20) 2005; 36 Goff (10.1016/j.atherosclerosis.2018.06.005_bib5) 2014; 129 Tattersall (10.1016/j.atherosclerosis.2018.06.005_bib26) 2014; 45 Ostling (10.1016/j.atherosclerosis.2018.06.005_bib23) 2007; 38 Carr (10.1016/j.atherosclerosis.2018.06.005_bib37) 2005; 234 van Engelen (10.1016/j.atherosclerosis.2018.06.005_bib39) 2014; 45 Barnett (10.1016/j.atherosclerosis.2018.06.005_bib34) 1997; 15 Bild (10.1016/j.atherosclerosis.2018.06.005_bib25) 2002; 156 Folsom (10.1016/j.atherosclerosis.2018.06.005_bib32) 2008; 168 Doonan (10.1016/j.atherosclerosis.2018.06.005_bib33) 2016; 64 Gepner (10.1016/j.atherosclerosis.2018.06.005_bib3) 2015; 8 Lal (10.1016/j.atherosclerosis.2018.06.005_bib35) 2002; 35 Mitchell (10.1016/j.atherosclerosis.2018.06.005_bib17) 2017; 43 Nicolaides (10.1016/j.atherosclerosis.2018.06.005_bib13) 2010; 52 Ruiz-Ares (10.1016/j.atherosclerosis.2018.06.005_bib19) 2011; 32 Spence (10.1016/j.atherosclerosis.2018.06.005_bib9) 2002; 33 Salem (10.1016/j.atherosclerosis.2018.06.005_bib14) 2014; 48 Lind (10.1016/j.atherosclerosis.2018.06.005_bib24) 2007; 195 Johnsen (10.1016/j.atherosclerosis.2018.06.005_bib11) 2007; 38 Goff (10.1016/j.atherosclerosis.2018.06.005_bib6) 2014; 129 Virmani (10.1016/j.atherosclerosis.2018.06.005_bib15) 2006; 59 Tattersall (10.1016/j.atherosclerosis.2018.06.005_bib30) 2015; 35 Gepner (10.1016/j.atherosclerosis.2018.06.005_bib29) 2015; 10 |
| References_xml | – volume: 48 start-page: 118 year: 2014 end-page: 125 ident: bib14 article-title: Identification of patients with a histologically unstable carotid plaque using ultrasonic plaque image analysis publication-title: Eur. J. Vasc. Endovasc. Surg. contributor: fullname: Moore – volume: 33 start-page: 2916 year: 2002 end-page: 2922 ident: bib9 article-title: Carotid plaque area: a tool for targeting and evaluating vascular preventive therapy publication-title: Stroke contributor: fullname: Galil – volume: 57 start-page: 609 year: 2013 end-page: 618 ident: bib18 article-title: The size of juxtaluminal hypoechoic area in ultrasound images of asymptomatic carotid plaques predicts the occurrence of stroke publication-title: J. Vasc. Surg. contributor: fullname: Sabetai – volume: 36 start-page: 741 year: 2005 end-page: 745 ident: bib20 article-title: Stratified gray-scale median analysis and color mapping of the carotid plaque: correlation with endarterectomy specimen hiostology of 28 patients publication-title: Stroke contributor: fullname: Djebaili – volume: 168 start-page: 1333 year: 2008 end-page: 1339 ident: bib32 article-title: Coronary artery calcification compared with carotid intima-media thickness in the prediction of cardiovascular disease incidence: the Multi-Ethnic Study of Atherosclerosis (MESA) publication-title: Arch. Intern. Med. contributor: fullname: Bild – volume: 15 start-page: 1512 year: 1995 end-page: 1531 ident: bib16 article-title: A definition of advanced types of atherosclerotic lesions and a histological classification of atherosclerosis : a report from the committee on vascular lesions of the council on Arteriosclerosis, American heart association publication-title: Arterioscler. Thromb. Vasc. Biol. contributor: fullname: Glagov – volume: 45 start-page: 3257 year: 2014 end-page: 3262 ident: bib26 article-title: Predictors of carotid thickness and plaque progression during a decade: the Multi-Ethnic Study of Atherosclerosis publication-title: Stroke contributor: fullname: Kaufman – volume: 39 start-page: 329 year: 2008 end-page: 335 ident: bib28 article-title: Risk factor associations with the presence of a lipid core in cartotid plaque of asymptomatic individuals using high-resolution MRI: the Multi-Ethnic Study of Atherosclerosis (MESA) publication-title: Stroke contributor: fullname: Folsom – volume: 11 start-page: 414 year: 1996 end-page: 416 ident: bib36 article-title: Histological verification of computerised carotid plaque charaterisation publication-title: Eur. J. Vasc. Endovasc. Surg. contributor: fullname: Nicolaides – volume: 135 start-page: e146 year: 2017 end-page: e603 ident: bib1 article-title: Heart disease and stroke statistics - 2017 update a report from the American heart association publication-title: Circulation contributor: fullname: Das – volume: 105 start-page: 2872 year: 2002 end-page: 2877 ident: bib8 article-title: Carotid plaques increase the risk of stroke and subtypes of cerebral infarction in asymptomatic elderly: the Rotterdam study publication-title: Circulation contributor: fullname: Witteman – volume: 234 start-page: 35 year: 2005 end-page: 43 ident: bib37 article-title: Calcified coronary artery plaque measurement with cardiac CT in population-based studies: standardized protocol of Multi-Ethnic Study of Atherosclerosis (MESA) and Coronary Artery Risk Development in Young Adults (CARDIA) study publication-title: Radiology contributor: fullname: Arad – volume: 4 start-page: 8 year: 2011 end-page: 15 ident: bib27 article-title: Cardiovascular imaging for assessing cardiovascular risk in asymptomatic men versus women: the Multi-Ethnic Study of Atherosclerosis (MESA) publication-title: Circ.Cardiovasc. Imaging contributor: fullname: Burke – volume: 64 start-page: 671 year: 2016 end-page: 677 ident: bib33 article-title: Plaque echodensity and textural features are associated with histologic carotid plaque instability publication-title: J. Vasc. Surg. contributor: fullname: Kyriacou – volume: 8 year: 2015 ident: bib3 article-title: Comparison of coronary artery calcium presence, carotid plaque presence, and carotid intima-media thickness for cardiovascular disease prediction in the Multi-Ethnic Study of Atherosclerosis publication-title: Circ.Cardiovasc. Imaging contributor: fullname: Blaha – volume: 66 start-page: 1643 year: 2015 end-page: 1653 ident: bib10 article-title: 10-year coronary heart disease risk prediction using coronary artery calcium and traditional risk factors: derivation in the MESA (Multi-Ethnic Study of Atherosclerosis) with validation in the HNR (Heinz Nixdorf Recall) study and the DHS (Dallas Heart Study) publication-title: J. Am. Coll. Cardiol. contributor: fullname: Post – volume: 55 start-page: 1600 year: 2010 end-page: 1607 ident: bib7 article-title: Carotid intima-media thickness and presence or absence of plaque improves prediction of coronary heart disease risk: the ARIC (Atherosclerosis Risk in Communities) study publication-title: J. Am. Coll. Cardiol. contributor: fullname: Hu – volume: 52 start-page: 1486 year: 2010 end-page: 1496 ident: bib13 article-title: Asymptomatic internal carotid artery stenosis and cerebrovascular risk stratification publication-title: J. Vasc. Surg. contributor: fullname: Sabetai – volume: 43 start-page: 129 year: 2017 end-page: 137 ident: bib17 article-title: Histopathologic validation of grayscale carotid plaque characteristics related to plaque vulnerability publication-title: Ultrasound Med. Biol. contributor: fullname: Wang – volume: 26 start-page: 69 year: 2016 end-page: 80 ident: bib38 article-title: Three-dimensional ultrasound of carotid plaque publication-title: Neuroimaging Clin. N. Am. contributor: fullname: Parraga – volume: 35 start-page: 649 year: 2004 end-page: 653 ident: bib40 article-title: Noninvasive phenotypes of atherosclerosis: similar windows but different views publication-title: Stroke contributor: fullname: Hegele – volume: 35 start-page: 661 year: 2008 end-page: 668 ident: bib22 article-title: Intensive lipid-lowering therapy ameliorates novel calcification markers and GSM score in patients with carotid stenosis publication-title: Eur. J. Vasc. Endovasc. Surg. contributor: fullname: Sailer – volume: 15 start-page: 49 year: 1997 end-page: 55 ident: bib34 article-title: Psychological stress and the progression of carotid artery disease publication-title: J. Hypertens. contributor: fullname: Jennings – volume: 10 year: 2015 ident: bib29 article-title: Carotid artery longitudinal displacement, cardiovascular disease and risk factors: the Multi-Ethnic Study of Atherosclerosis publication-title: PLoS One contributor: fullname: Kaufman – volume: 129 start-page: S74 year: 2014 end-page: S75 ident: bib6 article-title: 2013 ACC/AHA guideline on the assessment of cardiovascular risk: a report of the American college of cardiology/American heart association task force on practice guidelines publication-title: Erratum. Circulation contributor: fullname: Gibbons – volume: 6 year: 2017 ident: bib2 article-title: Comparison of carotid plaque score and coronary artery calcium score for predicting cardiovascular disease events: the Multi-Ethnic Study of Atherosclerosis publication-title: J Am Heart Assoc. contributor: fullname: Polak – volume: 12 start-page: 34 year: 2009 end-page: 38 ident: bib4 article-title: Use of carotid ultrasound to identify subclinical vascular disease and evaluate cardiovascular disease risk: summary and discussion of the American society of echocardiography consensus statement publication-title: Prev. Cardiol. contributor: fullname: Post – volume: 35 start-page: 1520 year: 2015 end-page: 1525 ident: bib31 article-title: Asthma predicts cardiovascular disease events: the Multi-Ethnic Study of Atherosclerosis publication-title: Arterioscler. Thromb. Vasc. Biol. contributor: fullname: Kaufman – volume: 129 start-page: S49 year: 2014 end-page: S73 ident: bib5 article-title: 2013 ACC/AHA guideline on the assessment of cardiovascular risk: a report of the American college of cardiology/American heart association task force on practice guidelines publication-title: Circulation contributor: fullname: D'Agostino – volume: 35 start-page: 1520 year: 2015 end-page: 1525 ident: bib30 article-title: Asthma predicts cardiovascular disease events: the Multi-Ethnic Study of Atherosclerosis. (online supplement) publication-title: Arterioscler. Thromb. Vasc. Biol. contributor: fullname: Kaufman – volume: 35 start-page: 1210 year: 2002 end-page: 1217 ident: bib35 article-title: Pixel distribution analysis of B-mode ultrasound scan images predicts histologic features of atherosclerotic carotid plaques publication-title: J. Vasc. Surg. contributor: fullname: Hameed – volume: 195 start-page: 411 year: 2007 end-page: 414 ident: bib24 article-title: The echogenicity of the intima-media complex in the common carotid artery is closely related to the echogenicity in plaques publication-title: Atherosclerosis contributor: fullname: Gustavsson – volume: 32 start-page: 535 year: 2011 end-page: 541 ident: bib19 article-title: Utility of the assessment of echogenicity in the identification of symptomatic carotid artery atheroma plaques in ischemic stroke patients publication-title: Cerebrovasc. Dis. contributor: fullname: Martinez-Martinez – volume: 38 start-page: 2074 year: 2007 end-page: 2078 ident: bib23 article-title: Increased echolucency of carotid plaques in patients with type 2 diabetes publication-title: Stroke contributor: fullname: Concalves – volume: 52 start-page: 69 year: 2010 end-page: 76 ident: bib21 article-title: Juxtaluminal hypoechoic area in ultrasonic images of carotid plaques and hemispheric symptoms publication-title: J. Vasc. Surg. contributor: fullname: Kakkos – volume: 24 start-page: 91 year: 2016 end-page: 95 ident: bib12 article-title: Evaluation of carotid plaque using ultrasound imaging publication-title: J. Cardiovasc. Ultrasound contributor: fullname: Park – volume: 59 start-page: S219 year: 2006 end-page: S227 ident: bib15 article-title: Histopathology of carotid atherosclerotic disease publication-title: Neurosurgery contributor: fullname: Kolodgie – volume: 156 start-page: 871 year: 2002 end-page: 881 ident: bib25 article-title: Multi-Ethnic Study of Atherosclerosis: objectives and design publication-title: Am. J. Epidemiol. contributor: fullname: Diez Roux – volume: 38 start-page: 2873 year: 2007 end-page: 2880 ident: bib11 article-title: Carotid atherosclerosis is a stronger predictor of myocardial infarction in women than in men a 6-year follow-up study of 6226 persons: the Tromsø study publication-title: Stroke contributor: fullname: Wilsgaard – volume: 45 start-page: 2695 year: 2014 end-page: 2701 ident: bib39 article-title: Three-dimensional carotid ultrasound plaque texture predicts vascular events publication-title: Stroke contributor: fullname: Fenster – volume: 234 start-page: 35 year: 2005 ident: 10.1016/j.atherosclerosis.2018.06.005_bib37 article-title: Calcified coronary artery plaque measurement with cardiac CT in population-based studies: standardized protocol of Multi-Ethnic Study of Atherosclerosis (MESA) and Coronary Artery Risk Development in Young Adults (CARDIA) study publication-title: Radiology doi: 10.1148/radiol.2341040439 contributor: fullname: Carr – volume: 105 start-page: 2872 year: 2002 ident: 10.1016/j.atherosclerosis.2018.06.005_bib8 article-title: Carotid plaques increase the risk of stroke and subtypes of cerebral infarction in asymptomatic elderly: the Rotterdam study publication-title: Circulation doi: 10.1161/01.CIR.0000018650.58984.75 contributor: fullname: Hollander – volume: 6 year: 2017 ident: 10.1016/j.atherosclerosis.2018.06.005_bib2 article-title: Comparison of carotid plaque score and coronary artery calcium score for predicting cardiovascular disease events: the Multi-Ethnic Study of Atherosclerosis publication-title: J Am Heart Assoc. contributor: fullname: Gepner – volume: 55 start-page: 1600 year: 2010 ident: 10.1016/j.atherosclerosis.2018.06.005_bib7 article-title: Carotid intima-media thickness and presence or absence of plaque improves prediction of coronary heart disease risk: the ARIC (Atherosclerosis Risk in Communities) study publication-title: J. Am. Coll. Cardiol. doi: 10.1016/j.jacc.2009.11.075 contributor: fullname: Nambi – volume: 26 start-page: 69 year: 2016 ident: 10.1016/j.atherosclerosis.2018.06.005_bib38 article-title: Three-dimensional ultrasound of carotid plaque publication-title: Neuroimaging Clin. N. Am. doi: 10.1016/j.nic.2015.09.006 contributor: fullname: Spence – volume: 129 start-page: S49 issue: 25 Suppl 2 year: 2014 ident: 10.1016/j.atherosclerosis.2018.06.005_bib5 article-title: 2013 ACC/AHA guideline on the assessment of cardiovascular risk: a report of the American college of cardiology/American heart association task force on practice guidelines publication-title: Circulation doi: 10.1161/01.cir.0000437741.48606.98 contributor: fullname: Goff – volume: 33 start-page: 2916 year: 2002 ident: 10.1016/j.atherosclerosis.2018.06.005_bib9 article-title: Carotid plaque area: a tool for targeting and evaluating vascular preventive therapy publication-title: Stroke doi: 10.1161/01.STR.0000042207.16156.B9 contributor: fullname: Spence – volume: 11 start-page: 414 year: 1996 ident: 10.1016/j.atherosclerosis.2018.06.005_bib36 article-title: Histological verification of computerised carotid plaque charaterisation publication-title: Eur. J. Vasc. Endovasc. Surg. doi: 10.1016/S1078-5884(96)80172-9 contributor: fullname: El-Barghouty – volume: 57 start-page: 609 year: 2013 ident: 10.1016/j.atherosclerosis.2018.06.005_bib18 article-title: The size of juxtaluminal hypoechoic area in ultrasound images of asymptomatic carotid plaques predicts the occurrence of stroke publication-title: J. Vasc. Surg. doi: 10.1016/j.jvs.2012.09.045 contributor: fullname: Kakkos – volume: 168 start-page: 1333 year: 2008 ident: 10.1016/j.atherosclerosis.2018.06.005_bib32 article-title: Coronary artery calcification compared with carotid intima-media thickness in the prediction of cardiovascular disease incidence: the Multi-Ethnic Study of Atherosclerosis (MESA) publication-title: Arch. Intern. Med. doi: 10.1001/archinte.168.12.1333 contributor: fullname: Folsom – volume: 45 start-page: 2695 year: 2014 ident: 10.1016/j.atherosclerosis.2018.06.005_bib39 article-title: Three-dimensional carotid ultrasound plaque texture predicts vascular events publication-title: Stroke doi: 10.1161/STROKEAHA.114.005752 contributor: fullname: van Engelen – volume: 45 start-page: 3257 year: 2014 ident: 10.1016/j.atherosclerosis.2018.06.005_bib26 article-title: Predictors of carotid thickness and plaque progression during a decade: the Multi-Ethnic Study of Atherosclerosis publication-title: Stroke doi: 10.1161/STROKEAHA.114.005669 contributor: fullname: Tattersall – volume: 12 start-page: 34 year: 2009 ident: 10.1016/j.atherosclerosis.2018.06.005_bib4 article-title: Use of carotid ultrasound to identify subclinical vascular disease and evaluate cardiovascular disease risk: summary and discussion of the American society of echocardiography consensus statement publication-title: Prev. Cardiol. doi: 10.1111/j.1751-7141.2008.00021.x contributor: fullname: Stein – volume: 35 start-page: 1210 year: 2002 ident: 10.1016/j.atherosclerosis.2018.06.005_bib35 article-title: Pixel distribution analysis of B-mode ultrasound scan images predicts histologic features of atherosclerotic carotid plaques publication-title: J. Vasc. Surg. doi: 10.1067/mva.2002.122888 contributor: fullname: Lal – volume: 195 start-page: 411 year: 2007 ident: 10.1016/j.atherosclerosis.2018.06.005_bib24 article-title: The echogenicity of the intima-media complex in the common carotid artery is closely related to the echogenicity in plaques publication-title: Atherosclerosis doi: 10.1016/j.atherosclerosis.2007.03.029 contributor: fullname: Lind – volume: 129 start-page: S74 issue: 25 Suppl 2 year: 2014 ident: 10.1016/j.atherosclerosis.2018.06.005_bib6 article-title: 2013 ACC/AHA guideline on the assessment of cardiovascular risk: a report of the American college of cardiology/American heart association task force on practice guidelines publication-title: Erratum. Circulation contributor: fullname: Goff – volume: 35 start-page: 1520 year: 2015 ident: 10.1016/j.atherosclerosis.2018.06.005_bib30 article-title: Asthma predicts cardiovascular disease events: the Multi-Ethnic Study of Atherosclerosis. (online supplement) publication-title: Arterioscler. Thromb. Vasc. Biol. doi: 10.1161/ATVBAHA.115.305452 contributor: fullname: Tattersall – volume: 15 start-page: 1512 year: 1995 ident: 10.1016/j.atherosclerosis.2018.06.005_bib16 article-title: A definition of advanced types of atherosclerotic lesions and a histological classification of atherosclerosis : a report from the committee on vascular lesions of the council on Arteriosclerosis, American heart association publication-title: Arterioscler. Thromb. Vasc. Biol. doi: 10.1161/01.ATV.15.9.1512 contributor: fullname: Stary – volume: 156 start-page: 871 year: 2002 ident: 10.1016/j.atherosclerosis.2018.06.005_bib25 article-title: Multi-Ethnic Study of Atherosclerosis: objectives and design publication-title: Am. J. Epidemiol. doi: 10.1093/aje/kwf113 contributor: fullname: Bild – volume: 64 start-page: 671 year: 2016 ident: 10.1016/j.atherosclerosis.2018.06.005_bib33 article-title: Plaque echodensity and textural features are associated with histologic carotid plaque instability publication-title: J. Vasc. Surg. doi: 10.1016/j.jvs.2016.03.423 contributor: fullname: Doonan – volume: 135 start-page: e146 year: 2017 ident: 10.1016/j.atherosclerosis.2018.06.005_bib1 article-title: Heart disease and stroke statistics - 2017 update a report from the American heart association publication-title: Circulation doi: 10.1161/CIR.0000000000000485 contributor: fullname: Benjamin – volume: 52 start-page: 69 year: 2010 ident: 10.1016/j.atherosclerosis.2018.06.005_bib21 article-title: Juxtaluminal hypoechoic area in ultrasonic images of carotid plaques and hemispheric symptoms publication-title: J. Vasc. Surg. doi: 10.1016/j.jvs.2010.02.265 contributor: fullname: Griffin – volume: 15 start-page: 49 year: 1997 ident: 10.1016/j.atherosclerosis.2018.06.005_bib34 article-title: Psychological stress and the progression of carotid artery disease publication-title: J. Hypertens. doi: 10.1097/00004872-199715010-00004 contributor: fullname: Barnett – volume: 39 start-page: 329 year: 2008 ident: 10.1016/j.atherosclerosis.2018.06.005_bib28 article-title: Risk factor associations with the presence of a lipid core in cartotid plaque of asymptomatic individuals using high-resolution MRI: the Multi-Ethnic Study of Atherosclerosis (MESA) publication-title: Stroke doi: 10.1161/STROKEAHA.107.498634 contributor: fullname: Wasserman – volume: 59 start-page: S219 issue: 5 Suppl 3 year: 2006 ident: 10.1016/j.atherosclerosis.2018.06.005_bib15 article-title: Histopathology of carotid atherosclerotic disease publication-title: Neurosurgery contributor: fullname: Virmani – volume: 36 start-page: 741 year: 2005 ident: 10.1016/j.atherosclerosis.2018.06.005_bib20 article-title: Stratified gray-scale median analysis and color mapping of the carotid plaque: correlation with endarterectomy specimen hiostology of 28 patients publication-title: Stroke doi: 10.1161/01.STR.0000157599.10026.ad contributor: fullname: Sztajzel – volume: 43 start-page: 129 year: 2017 ident: 10.1016/j.atherosclerosis.2018.06.005_bib17 article-title: Histopathologic validation of grayscale carotid plaque characteristics related to plaque vulnerability publication-title: Ultrasound Med. Biol. doi: 10.1016/j.ultrasmedbio.2016.08.011 contributor: fullname: Mitchell – volume: 4 start-page: 8 year: 2011 ident: 10.1016/j.atherosclerosis.2018.06.005_bib27 article-title: Cardiovascular imaging for assessing cardiovascular risk in asymptomatic men versus women: the Multi-Ethnic Study of Atherosclerosis (MESA) publication-title: Circ.Cardiovasc. Imaging doi: 10.1161/CIRCIMAGING.110.959403 contributor: fullname: Jain – volume: 35 start-page: 661 year: 2008 ident: 10.1016/j.atherosclerosis.2018.06.005_bib22 article-title: Intensive lipid-lowering therapy ameliorates novel calcification markers and GSM score in patients with carotid stenosis publication-title: Eur. J. Vasc. Endovasc. Surg. doi: 10.1016/j.ejvs.2007.12.011 contributor: fullname: Kadoglou – volume: 52 start-page: 1486 year: 2010 ident: 10.1016/j.atherosclerosis.2018.06.005_bib13 article-title: Asymptomatic internal carotid artery stenosis and cerebrovascular risk stratification publication-title: J. Vasc. Surg. doi: 10.1016/j.jvs.2010.07.021 contributor: fullname: Nicolaides – volume: 10 year: 2015 ident: 10.1016/j.atherosclerosis.2018.06.005_bib29 article-title: Carotid artery longitudinal displacement, cardiovascular disease and risk factors: the Multi-Ethnic Study of Atherosclerosis publication-title: PLoS One doi: 10.1371/journal.pone.0142138 contributor: fullname: Gepner – volume: 66 start-page: 1643 year: 2015 ident: 10.1016/j.atherosclerosis.2018.06.005_bib10 publication-title: J. Am. Coll. Cardiol. doi: 10.1016/j.jacc.2015.08.035 contributor: fullname: McClelland – volume: 48 start-page: 118 year: 2014 ident: 10.1016/j.atherosclerosis.2018.06.005_bib14 article-title: Identification of patients with a histologically unstable carotid plaque using ultrasonic plaque image analysis publication-title: Eur. J. Vasc. Endovasc. Surg. doi: 10.1016/j.ejvs.2014.05.015 contributor: fullname: Salem – volume: 24 start-page: 91 year: 2016 ident: 10.1016/j.atherosclerosis.2018.06.005_bib12 article-title: Evaluation of carotid plaque using ultrasound imaging publication-title: J. Cardiovasc. Ultrasound doi: 10.4250/jcu.2016.24.2.91 contributor: fullname: Park – volume: 35 start-page: 649 year: 2004 ident: 10.1016/j.atherosclerosis.2018.06.005_bib40 article-title: Noninvasive phenotypes of atherosclerosis: similar windows but different views publication-title: Stroke doi: 10.1161/01.STR.0000116103.19029.DB contributor: fullname: Spence – volume: 32 start-page: 535 year: 2011 ident: 10.1016/j.atherosclerosis.2018.06.005_bib19 article-title: Utility of the assessment of echogenicity in the identification of symptomatic carotid artery atheroma plaques in ischemic stroke patients publication-title: Cerebrovasc. Dis. doi: 10.1159/000330654 contributor: fullname: Ruiz-Ares – volume: 8 year: 2015 ident: 10.1016/j.atherosclerosis.2018.06.005_bib3 article-title: Comparison of coronary artery calcium presence, carotid plaque presence, and carotid intima-media thickness for cardiovascular disease prediction in the Multi-Ethnic Study of Atherosclerosis publication-title: Circ.Cardiovasc. Imaging doi: 10.1161/CIRCIMAGING.114.002262 contributor: fullname: Gepner – volume: 38 start-page: 2074 year: 2007 ident: 10.1016/j.atherosclerosis.2018.06.005_bib23 article-title: Increased echolucency of carotid plaques in patients with type 2 diabetes publication-title: Stroke doi: 10.1161/STROKEAHA.106.480830 contributor: fullname: Ostling – volume: 38 start-page: 2873 year: 2007 ident: 10.1016/j.atherosclerosis.2018.06.005_bib11 article-title: Carotid atherosclerosis is a stronger predictor of myocardial infarction in women than in men a 6-year follow-up study of 6226 persons: the Tromsø study publication-title: Stroke doi: 10.1161/STROKEAHA.107.487264 contributor: fullname: Johnsen – volume: 35 start-page: 1520 year: 2015 ident: 10.1016/j.atherosclerosis.2018.06.005_bib31 article-title: Asthma predicts cardiovascular disease events: the Multi-Ethnic Study of Atherosclerosis publication-title: Arterioscler. Thromb. Vasc. Biol. doi: 10.1161/ATVBAHA.115.305452 contributor: fullname: Tattersall |
| SSID | ssj0004718 |
| Score | 2.5090609 |
| Snippet | It is not known if ultrasound carotid plaque features are associated with cardiovascular disease (CVD) risk factors or if they predict future CVD events.
We... It is not known if ultrasound carotid plaque features are associated with cardiovascular disease (CVD) risk factors or if they predict future CVD... |
| SourceID | pubmedcentral proquest crossref pubmed elsevier |
| SourceType | Open Access Repository Aggregation Database Index Database Publisher |
| StartPage | 195 |
| SubjectTerms | Aged Aged, 80 and over Cardiovascular disease Carotid Arteries - diagnostic imaging Carotid Artery Diseases - diagnostic imaging Carotid Artery Diseases - ethnology Carotid Intima-Media Thickness Carotid ultrasound Cerebrovascular Disorders - diagnosis Cerebrovascular Disorders - ethnology Coronary Disease - diagnosis Coronary Disease - ethnology Echogenicity Female Humans Male Middle Aged Plaque Plaque, Atherosclerotic Predictive Value of Tests Prevalence Prognosis Risk Assessment Risk Factors United States - epidemiology |
| Title | Ultrasound carotid plaque features, cardiovascular disease risk factors and events: The Multi-Ethnic Study of Atherosclerosis |
| URI | https://dx.doi.org/10.1016/j.atherosclerosis.2018.06.005 https://www.ncbi.nlm.nih.gov/pubmed/29970256 https://www.proquest.com/docview/2064242610/abstract/ https://pubmed.ncbi.nlm.nih.gov/PMC7436944 |
| Volume | 276 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1LT4NAEJ5oTRovxrf1lTXRmyjIsognG1NTNfZkk97IQmcjxtDG4sGD_nZnYFGrHky8kMDCsjDsPNhvvgHY1xrRNSeeo6MIHSlTdLRUyqF4SKUh0w8pTnC-7aluX14PgsEMXNS5MAyrtLq_0umltrZHju3bPB5nGef40mzzmJCO1DDZ6VmYI3MkZQPm2lc33d5nemToVQqZ0Qh0QRMOPmFepZ81mlCvtM2YwNurGD25oN3vpuqnK_odUfnFRF0uwoL1LUW7Gv4SzGC-DM1bu3q-Aq_9R7pswoWUBJfrKbKhGD9quokwWBJ8Tg654QtAVdgFHMEQdGGL8whNHZTMT5MzQd-ZKLN4nU5xn2epYGTiixgZ0Z5-5lXoX3buLrqOLb_gpBQGFY7SxvcTD7UvE9KC7AugIZn7kn-chuRqGS9IE32qUaohknQjbYzSSRQF6dBz_TVo5KMcN0CchGmCrqRoMokk8spcqIIhpkb5LkbSb4Gq33Q8rlg24hp-9hB_E1HMIopLOF7QgvNaLvHUZxOTRfhrF3u1PGOaWrxeonMcPfNJFJxxiOm2YL2S78foyIqH7C62IJyS_McJTNs93ZJn9yV9N_lsKpJy8_9D34J53qsgb9vQKJ6ecYd8pCLZhdmjN2_XzoR3MCcYzg |
| link.rule.ids | 230,315,786,790,891,4521,24144,27955,27956,45618,45712 |
| linkProvider | Elsevier |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1LT9tAEB5BIgEX1FJoA31spXLDwo7Xa8ypURQUHskpkbit1s6sMEJORMyBA_-dGXsNhPZQqRcfvOv12uOdh_ebbwB-GYPo227gmSRBT8oMPSOV8igeUlnM9EOKE5xHYzWcyovr6HoN-k0uDMMqne6vdXqlrd2ZY_c2jxd5zjm-tNoCJqQjNUx2eh3aMoqDbgvavfPL4fg1PTIOaoXMaAS6YAMOX2FelZ81X9KodMyZwDuoGT25oN3fTdWfruh7ROUbE3X2Abadbyl69fQ_whoWO7Axcrvnn-BpekeXLbmQkuByPWU-E4s7QzcRFiuCz-URN7wBqAq3gSMYgi5ccR5haICK-Wl5Kug7E1UWrzcob4o8E4xMfBRzK3qrz7wL07PBpD_0XPkFL6MwqPSUsWGYBmhCmZIWZF8ALck8lPzjNCZXywZRlpoTg1LNkKSbGGuVSZMkymaBH-5Bq5gX-AVEN85S9CVFk2kikXfmYhXNMLMq9DGRYQdU86b1ombZ0A387Fa_E5FmEekKjhd14HcjF73y2WiyCP86xM9GnpqWFu-XmALnD9yJgjMOMf0OfK7l-zI7suIxu4sdiFck_9KBabtXW4r8pqLvJp9NJVLu___Uf8DmcDK60lfn48sD2OKWGv72FVrl_QN-I3-pTL-79fAM6goavg |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Ultrasound+Carotid+Plaque+Features%2C+Cardiovascular+Disease+Risk+Factors+and+Events%3A+The+Multi-Ethnic+Study+of+Atherosclerosis&rft.jtitle=Atherosclerosis&rft.au=Mitchell%2C+Carol&rft.au=Korcarz%2C+Claudia+E.&rft.au=Gepner%2C+Adam+D.&rft.au=Kaufman%2C+Joel+D.&rft.date=2018-09-01&rft.issn=0021-9150&rft.eissn=1879-1484&rft.volume=276&rft.spage=195&rft.epage=202&rft_id=info:doi/10.1016%2Fj.atherosclerosis.2018.06.005&rft_id=info%3Apmid%2F29970256&rft.externalDBID=PMC7436944 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0021-9150&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0021-9150&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0021-9150&client=summon |