Tranexamic Acid for Adults with Melasma: A Systematic Review and Meta-Analysis

• Published in: BioMed research international Vol. 2018; no. 2018; pp. 1 - 13
• Main Authors: Wang, Xiao-Wei, Zhao, Qi-Ming, Zhao, Wan-Yi, Fang, Qing-Qing, Tan, Wei-Qiang, Zhang, Lei, Gao, Jie
• Format: Journal Article
• Language: English
• Published: Cairo, Egypt Hindawi Publishing Corporation 01.01.2018; Hindawi; John Wiley & Sons, Inc
• Subjects: Acids; Adolescent; Adult; Adults; Analysis; Antifibrinolytic agents; Bias; Binding sites; Care and treatment; Case-Control Studies; Collaboration; Confidence intervals; Dermatitis; Dermatology; Erythema; Health aspects; Humans; Irritation; Melanin; Melanins - metabolism; Melanosis; Melanosis - drug therapy; Meta-analysis; Middle Aged; Pigmentation; Publication Bias; Randomized Controlled Trials as Topic; Review; Severity of Illness Index; Side effects; Skin; Statistical analysis; Studies; Systematic review; Tranexamic acid; Tranexamic Acid - therapeutic use; Young Adult; China; United States > US

Objective. Melasma is a highly prevalent, chronic, and pigmentary disorder. This systematic review aims to evaluate the efficacy and safety of tranexamic acid (TA) for the treatment of adults with melasma. Methods. We independently searched 3 databases from beginning to 26 April, 2018. The study inc...