Vitamin D Modulates Hematological Parameters and Cell Migration into Peritoneal and Pulmonary Cavities in Alloxan-Diabetic Mice

• Published in: BioMed research international Vol. 2017; no. 2017; pp. 1 - 10
• Main Authors: Martins, Joilson O., Ferreira, Sabrina S., Nunes, Fernanda P. B., Nolasco, Eduardo L., Tessaro, Fernando H. G., Fieri, Isis, Bella, Leonardo M., Azevedo, Carolina B.
• Format: Journal Article
• Language: English
• Published: Cairo, Egypt Hindawi Publishing Corporation 01.01.2017; Hindawi; John Wiley & Sons, Inc; Hindawi Limited
• Subjects: Alfacalcidol; Alkaline Phosphatase - blood; Animals; Aspartate Aminotransferases - blood; Biomedical research; Calcifediol; Cell migration; Cell Movement - drug effects; Cholecalciferol - administration & dosage; Diabetes; Diabetes Mellitus, Experimental - blood; Diabetes Mellitus, Experimental - diet therapy; Diabetes Mellitus, Experimental - pathology; Dietary Supplements; Enzymes; Erythrocyte Count; Health aspects; Hematology; Humans; Hyperglycemia; Kidney diseases; Leukocyte Count; Liver; Liver - drug effects; Liver - metabolism; Lung - drug effects; Lung - metabolism; Metabolism; Mice; Mice, Inbred NOD - metabolism; Morphology; Peritoneal Cavity - pathology; Pharmaceutical sciences; Physiological aspects; Physiology; Rodents; Studies; Type 1 diabetes; Vitamin D; Vitamin D - analogs & derivatives; Vitamin D - blood; Vitamin D - metabolism; Brazil

Background/Aims. The effects of cholecalciferol supplementation on the course of diabetes in humans and animals need to be better understood. Therefore, this study investigated the effect of short-term cholecalciferol supplementation on biochemical and hematological parameters in mice. Methods. Male...