Spectral and 3D model studies of the interaction of orphan human cytochrome P450 2U1 with substrates and ligands - Dhers, Laura; Pietrancosta, Nicolas; Ducassou, Lionel; Ramassamy, Booma; Dairou, Julien; Jaouen, Maryse; André, François; Mansuy, Daniel; Boucher, Jean-Luc (Biochimica et biophysica acta. General subjects, 2017)
Keywords: active sites; arachidonic acid; Arachidonic Acid - chemistry; Arachidonic Acid - metabolism; Arachidonic acid derivatives; Arachidonic Acids - chemistry; Arachidonic Acids - metabolism; Biocatalysis; cytochrome P-450; Cytochrome P450 Family 2 - chemistry; Cytochrome P450 Family 2 - metabolism; Debrisoquin - chemistry; electron paramagnetic resonance spectroscopy; Electron Spin Resonance Spectroscopy; Escherichia coli; Expression in E. coli; genome; Humans; Imidazole ligands; Imidazoles - chemistry; ketoconazole; Lauric Acids - chemistry; Life Sciences; Ligands; miconazole; Models, Molecular; Molecular docking; Molecular Docking Simulation; molecular models; Orphan cytochrome P450 2U1; Oxidation-Reduction; Protein Binding; pyridines; Pyridines - chemistry; Recombinant Proteins - chemistry; Recombinant Proteins - metabolism; Serotonin - analogs & derivatives; Serotonin - chemistry; Serotonin - metabolism; spectral analysis; Spectrophotometry, Ultraviolet; Substrate Specificity; xenobiotics; AA; Deb; Im; Arachidonic acid derivatives; Terfimidazole; Molecular docking; BSA; AS; Orphan cytochrome P450 2U1; LA; IPTG; CYP; DLPC; Imidazole ligands; Expression in E. coli; B3S; LSOD