Survival Mechanisms and Influence Factors of Circulating Tumor Cells

• Published in: BioMed research international Vol. 2018; no. 2018; pp. 1 - 9
• Main Authors: Zhang, Xiao-Feng, Lin, Mou-Bin, Bie, Ya-Qin, Wang, Ai-Li, Li, Xi-Feng, Peng, Jian, Wang, Wen-Chao, Shi, Le-Hua
• Format: Journal Article
• Language: English
• Published: Cairo, Egypt Hindawi Publishing Corporation 01.01.2018; Hindawi; John Wiley & Sons, Inc
• Subjects: Anoikis; Anoikis - genetics; Apoptosis; Biology; Biomarkers; Biomarkers, Tumor - blood; Blood circulation; Breast cancer; Cancer; Cellular Microenvironment - genetics; Chemotherapy; Colorectal cancer; Cytokines; Cytokines - blood; Development and progression; Diseases; Epidermal growth factor; Gene amplification; Gene expression; Humans; Immune system; Kinases; Medical prognosis; Medical research; Metastases; Metastasis; Neoplasm Metastasis; Neoplasm Recurrence, Local - blood; Neoplasm Recurrence, Local - genetics; Neoplasm Recurrence, Local - pathology; Neoplasms - blood; Neoplasms - genetics; Neoplasms - pathology; Neoplastic Cells, Circulating - pathology; Oncology; Peripheral blood; Platelets; Prognosis; Relapse; Review; Shear strength; Shear stress; Signal transduction; Survival; Tumor cells; Tumors

Circulating tumor cells (CTCs) are cancer cells shed from either the primary tumor or its metastases that circulate in the peripheral blood. The CTCs are regarded as the source of tumor recurrence and metastasis and speculated as the indicators of residual tumors, thereby indicating a poor prognosis...