Antifibrotic Effect of Marine Ovothiol in an In Vivo Model of Liver Fibrosis

• Published in: Oxidative medicine and cellular longevity Vol. 2018; no. 2018; pp. 1 - 10
• Main Authors: Palumbo, Anna, Lembo, Vincenzo, D’Argenio, Giuseppe, Brancaccio, Mariarita, Castellano, Immacolata
• Format: Journal Article
• Language: English
• Published: Cairo, Egypt Hindawi Publishing Corporation 01.01.2018; Hindawi; John Wiley & Sons, Inc
• Subjects: Amino acids; Apoptosis; Aprotinin; Autophagy; Bone morphogenetic proteins; Carbon tetrachloride; Chemistry; Enzymes; Ethylenediaminetetraacetic acid; Fibrosis; Functional foods & nutraceuticals; Liver; Liver diseases; Natural products; Pharmaceuticals; Sulfur compounds; Transforming growth factors

Liver fibrosis is a complex process caused by chronic hepatic injury, which leads to an excessive increase in extracellular matrix protein accumulation and fibrogenesis. Several natural products, including sulfur-containing compounds, have been investigated for their antifibrotic effects; however, t...