Olive ( Olea europaea) leaf extract effective in patients with stage-1 hypertension: Comparison with Captopril

• Published in: Phytomedicine (Stuttgart) Vol. 18; no. 4; pp. 251 - 258
• Main Authors: Susalit, Endang, Agus, Nafrialdi, Effendi, Imam, Tjandrawinata, Raymond R., Nofiarny, Dwi, Perrinjaquet-Moccetti, Tania, Verbruggen, Marian
• Format: Journal Article
• Language: English
• Published: Germany Elsevier GmbH 15.02.2011; Urban & Fischer Verlag
• Subjects: Adult; Angiotensin-Converting Enzyme Inhibitors - pharmacology; Angiotensin-Converting Enzyme Inhibitors - therapeutic use; Antihypertensive Agents - pharmacology; Antihypertensive Agents - therapeutic use; antihypertensive effect; Blood pressure; Blood Pressure - drug effects; Captopril; Captopril - pharmacology; Captopril - therapeutic use; Chemical properties; Diagnosis; diastolic blood pressure; Dose-Response Relationship, Drug; Double-Blind Method; Double-blind randomized study; Drug therapy; Female; Health aspects; Humans; Hypertension; Hypertension - drug therapy; Hypertension - physiopathology; leaf extracts; Lipids - blood; Male; Materia medica, Vegetable; Middle Aged; Olea - chemistry; Olea europaea; Oleuropein; Olive; Olive leaf; patients; Plant extracts; Plant Extracts - pharmacology; Plant Extracts - therapeutic use; Plant Leaves - chemistry; Properties; Stage-1; systolic blood pressure; triacylglycerols; Switzerland; Hypertension; Olive leaf; Olea europaea; Oleuropein; Captopril; Blood pressure; Double-blind randomized study; Stage-1

A double-blind, randomized, parallel and active-controlled clinical study was conducted to evaluate the anti-hypertensive effect as well as the tolerability of Olive leaf extract in comparison with Captopril in patients with stage-1 hypertension. Additionally, this study also investigated the hypoli...