Computed tomography assessment of lung structure in patients undergoing cardiac surgery with cardiopulmonary bypass
Hypoxemia is a frequent complication after coronary artery bypass graft (CABG) with cardiopulmonary bypass (CPB), usually attributed to atelectasis. Using computed tomography (CT), we investigated postoperative pulmonary alterations and their impact on blood oxygenation. Eighteen non-hypoxemic patie...
Saved in:
| Published in | Brazilian journal of medical and biological research Vol. 44; no. 6; pp. 598 - 605 |
|---|---|
| Main Authors | , , , , , , , , |
| Format | Journal Article |
| Language | English Portuguese |
| Published |
Brazil
Associação Brasileira de Divulgação Científica
01.06.2011
|
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | Hypoxemia is a frequent complication after coronary artery bypass graft (CABG) with cardiopulmonary bypass (CPB), usually attributed to atelectasis. Using computed tomography (CT), we investigated postoperative pulmonary alterations and their impact on blood oxygenation. Eighteen non-hypoxemic patients (15 men and 3 women) with normal cardiac function scheduled for CABG under CPB were studied. Hemodynamic measurements and blood samples were obtained before surgery, after intubation, after CPB, at admission to the intensive care unit, and 12, 24, and 48 h after surgery. Pre- and postoperative volumetric thoracic CT scans were acquired under apnea conditions after a spontaneous expiration. Data were analyzed by the paired Student t-test and one-way repeated measures analysis of variance. Mean age was 63 ± 9 years. The PaO2/FiO2 ratio was significantly reduced after anesthesia induction, reaching its nadir after CPB and partially improving 12 h after surgery. Compared to preoperative CT, there was a 31% postoperative reduction in pulmonary gas volume (P < 0.001) while tissue volume increased by 19% (P < 0.001). Non-aerated lung increased by 253 ± 97 g (P < 0.001), from 3 to 27%, after surgery and poorly aerated lung by 72 ± 68 g (P < 0.001), from 24 to 27%, while normally aerated lung was reduced by 147 ± 119 g (P < 0.001), from 72 to 46%. No correlations (Pearson) were observed between PaO2/FiO2 ratio or shunt fraction at 24 h postoperatively and postoperative lung alterations. The data show that lung structure is profoundly modified after CABG with CPB. Taken together, multiple changes occurring in the lungs contribute to postoperative hypoxemia rather than atelectasis alone. |
|---|---|
| AbstractList | Hypoxemia is a frequent complication after coronary artery bypass graft (CABG) with cardiopulmonary bypass (CPB), usually attributed to atelectasis. Using computed tomography (CT), we investigated postoperative pulmonary alterations and their impact on blood oxygenation. Eighteen non-hypoxemic patients (15 men and 3 women) with normal cardiac function scheduled for CABG under CPB were studied. Hemodynamic measurements and blood samples were obtained before surgery, after intubation, after CPB, at admission to the intensive care unit, and 12, 24, and 48 h after surgery. Pre- and postoperative volumetric thoracic CT scans were acquired under apnea conditions after a spontaneous expiration. Data were analyzed by the paired Student t-test and one-way repeated measures analysis of variance. Mean age was 63 ± 9 years. The PaO2/FiO2 ratio was significantly reduced after anesthesia induction, reaching its nadir after CPB and partially improving 12 h after surgery. Compared to preoperative CT, there was a 31% postoperative reduction in pulmonary gas volume (P < 0.001) while tissue volume increased by 19% (P < 0.001). Non-aerated lung increased by 253 ± 97 g (P < 0.001), from 3 to 27%, after surgery and poorly aerated lung by 72 ± 68 g (P < 0.001), from 24 to 27%, while normally aerated lung was reduced by 147 ± 119 g (P < 0.001), from 72 to 46%. No correlations (Pearson) were observed between PaO2/FiO2 ratio or shunt fraction at 24 h postoperatively and postoperative lung alterations. The data show that lung structure is profoundly modified after CABG with CPB. Taken together, multiple changes occurring in the lungs contribute to postoperative hypoxemia rather than atelectasis alone. Hypoxemia is a frequent complication after coronary artery bypass graft (CABG) with cardiopulmonary bypass (CPB), usually attributed to atelectasis. Using computed tomography (CT), we investigated postoperative pulmonary alterations and their impact on blood oxygenation. Eighteen non-hypoxemic patients (15 men and 3 women) with normal cardiac function scheduled for CABG under CPB were studied. Hemodynamic measurements and blood samples were obtained before surgery, after intubation, after CPB, at admission to the intensive care unit, and 12, 24, and 48 h after surgery. Pre- and postoperative volumetric thoracic CT scans were acquired under apnea conditions after a spontaneous expiration. Data were analyzed by the paired Student t-test and one-way repeated measures analysis of variance. Mean age was 63 plus or minus 9 years. The PaO sub(2)/FiO sub(2) ratio was significantly reduced after anesthesia induction, reaching its nadir after CPB and partially improving 12 h after surgery. Compared to preoperative CT, there was a 31% postoperative reduction in pulmonary gas volume (P < 0.001) while tissue volume increased by 19% (P < 0.001). Non-aerated lung increased by 253 plus or minus 97 g (P < 0.001), from 3 to 27%, after surgery and poorly aerated lung by 72 plus or minus 68 g (P < 0.001), from 24 to 27%, while normally aerated lung was reduced by 147 plus or minus 119 g (P < 0.001), from 72 to 46%. No correlations (Pearson) were observed between PaO sub(2)/FiO sub(2) ratio or shunt fraction at 24 h postoperatively and postoperative lung alterations. The data show that lung structure is profoundly modified after CABG with CPB. Taken together, multiple changes occurring in the lungs contribute to postoperative hypoxemia rather than atelectasis alone. Hypoxemia is a frequent complication after coronary artery bypass graft (CABG) with cardiopulmonary bypass (CPB), usually attributed to atelectasis. Using computed tomography (CT), we investigated postoperative pulmonary alterations and their impact on blood oxygenation. Eighteen non-hypoxemic patients (15 men and 3 women) with normal cardiac function scheduled for CABG under CPB were studied. Hemodynamic measurements and blood samples were obtained before surgery, after intubation, after CPB, at admission to the intensive care unit, and 12, 24, and 48 h after surgery. Pre- and postoperative volumetric thoracic CT scans were acquired under apnea conditions after a spontaneous expiration. Data were analyzed by the paired Student t-test and one-way repeated measures analysis of variance. Mean age was 63 ± 9 years. The PaO2/FiO2 ratio was significantly reduced after anesthesia induction, reaching its nadir after CPB and partially improving 12 h after surgery. Compared to preoperative CT, there was a 31% postoperative reduction in pulmonary gas volume (P < 0.001) while tissue volume increased by 19% (P < 0.001). Non-aerated lung increased by 253 ± 97 g (P < 0.001), from 3 to 27%, after surgery and poorly aerated lung by 72 ± 68 g (P < 0.001), from 24 to 27%, while normally aerated lung was reduced by 147 ± 119 g (P < 0.001), from 72 to 46%. No correlations (Pearson) were observed between PaO2/FiO2 ratio or shunt fraction at 24 h postoperatively and postoperative lung alterations. The data show that lung structure is profoundly modified after CABG with CPB. Taken together, multiple changes occurring in the lungs contribute to postoperative hypoxemia rather than atelectasis alone. |
| Author | Rodrigues, R R Rouby, J-J Fukuda, M J Malbouisson, L M S Neves, F H Auler, J O Carmona, M J Pelosi, P Sawada, A Y |
| AuthorAffiliation | Universidade de São Paulo Université Pierre et Marie Curie Università degli Studi dell'Insubria |
| AuthorAffiliation_xml | – name: Universidade de São Paulo – name: Université Pierre et Marie Curie – name: Università degli Studi dell'Insubria |
| Author_xml | – sequence: 1 givenname: R R surname: Rodrigues fullname: Rodrigues, R R organization: Divisão de Anestesia, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, Av. Enéas C. Aguiar 25, São Paulo, SP, Brazil – sequence: 2 givenname: A Y surname: Sawada fullname: Sawada, A Y – sequence: 3 givenname: J-J surname: Rouby fullname: Rouby, J-J – sequence: 4 givenname: M J surname: Fukuda fullname: Fukuda, M J – sequence: 5 givenname: F H surname: Neves fullname: Neves, F H – sequence: 6 givenname: M J surname: Carmona fullname: Carmona, M J – sequence: 7 givenname: P surname: Pelosi fullname: Pelosi, P – sequence: 8 givenname: J O surname: Auler fullname: Auler, J O – sequence: 9 givenname: L M S surname: Malbouisson fullname: Malbouisson, L M S |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/21519640$$D View this record in MEDLINE/PubMed |
| BookMark | eNp9Ustu1DAUtVARnRZ-AbKDTcq14zy8RCMelSqxAKTuLMe-ST1K4uCH0Pw9bjMMCyQWlq3jc47v9blX5GJxCxLyhsINrQW8_wYUoOxacc-A5mNbAwDvnpEd5ZSXvKL3F2R3Jl2SqxAOAKwGTl-QS0ZrKhoOOxL2bl5TRFNEN7vRq_XhWKgQMIQZl1i4oZjSMhYh-qRj8ljYpVhVtPkyFGkx6EdnM0Erb6zSRUh-RH8sftn4sIFuTdPsFpXB_rhm75fk-aCmgK9O-zX58enj9_2X8u7r59v9h7tScyFiSdHwqhYmN8CaSrfUCNapiiFTKNjQ5oZbbnouWlHnD-hBq9p0A-dVhwiiq67J7eZrnDrI1ds51yCdsvIJcH6UykerJ5QdVB2gFo0aDO8r7I1BrAYNTdOzFursdbN5BW1xcvLgkl9y8fIpCfk3CWjyojwL3m6C1bufCUOUsw0ap0kt6FLIipxAlzPIzHf_ZWYzwWjLukdqu1G1dyF4HM5dUZCPg_FPOafByMrXp0dSP6M56_5MQvUb_Au08g |
| CitedBy_id | crossref_primary_10_1007_s00101_012_2083_4 crossref_primary_10_1177_02676591211052162 crossref_primary_10_1053_j_jvca_2017_09_013 crossref_primary_10_3390_jcm10153262 crossref_primary_10_1186_1749_8090_8_208 crossref_primary_10_52547_jccs_3_4_155 crossref_primary_10_1097_MD_0000000000006253 crossref_primary_10_1213_ANE_0000000000001118 crossref_primary_10_1097_HCR_0000000000000234 crossref_primary_10_1097_EJA_0000000000001022 crossref_primary_10_1007_s10753_013_9730_z crossref_primary_10_1371_journal_pone_0078643 |
| Cites_doi | 10.3949/ccjm.25.2.65 10.1016/S0003-4975(03)00347-3 10.1164/ajrccm.158.5.9802101 10.1097/00003643-200404000-00008 10.1097/00000542-199711000-00020 10.1164/ajrccm.158.5.9802003 10.1016/1010-7940(91)90078-X 10.1177/026765919701200605 10.1055/s-2000-8896 10.1111/j.1399-6576.1992.tb03568.x 10.1007/s001340100860 10.1016/S0954-6111(97)90010-X 10.1097/00000542-199808000-00013 10.1590/S0066-782X2003000300006 10.1378/chest.119.1.31 10.1164/ajrccm.149.1.8111603 10.1016/S0003-4975(99)00781-X 10.1378/chest.104.2.434 |
| ContentType | Journal Article |
| Copyright | This work is licensed under a Creative Commons Attribution 4.0 International License. |
| Copyright_xml | – notice: This work is licensed under a Creative Commons Attribution 4.0 International License. |
| DBID | CGR CUY CVF ECM EIF NPM AAYXX CITATION 7QO 8FD FR3 P64 7X8 GPN DOA |
| DOI | 10.1590/S0100-879X2011007500048 |
| DatabaseName | Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed CrossRef Biotechnology Research Abstracts Technology Research Database Engineering Research Database Biotechnology and BioEngineering Abstracts MEDLINE - Academic SciELO DOAJ Directory of Open Access Journals |
| DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) CrossRef Engineering Research Database Biotechnology Research Abstracts Technology Research Database Biotechnology and BioEngineering Abstracts MEDLINE - Academic |
| DatabaseTitleList | MEDLINE Engineering Research Database MEDLINE - Academic |
| Database_xml | – sequence: 1 dbid: DOA name: DOAJ Directory of Open Access Journals url: https://www.doaj.org/ sourceTypes: Open Website – sequence: 2 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 3 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine Biology |
| EISSN | 1414-431X 0100-879X |
| EndPage | 605 |
| ExternalDocumentID | oai_doaj_org_article_80380ec96afd4b3ebddee3fc066b2705 S0100_879X2011000600014 10_1590_S0100_879X2011007500048 21519640 |
| Genre | Research Support, Non-U.S. Gov't Journal Article |
| GroupedDBID | --- 23N 2WC 53G 5GY 5VS 6J9 ABIVO ABXHO ACGFO ADBBV ADRAZ AENEX AFPKN AIAGR ALMA_UNASSIGNED_HOLDINGS AOIJS APOWU AZFZN BAWUL BCNDV C1A CGR CS3 CUY CVF DIK E3Z EBD EBS ECM EIF EJD EMOBN FRP GROUPED_DOAJ GX1 HYE IAO IEA IHR IHW INF INH INR IPNFZ ITC KQ8 M48 M~E NPM OK1 P2P P6G PGMZT PV9 RIG RNS RPM RSC RZL SCD SV3 TR2 TUS W2D XSB ZXP AAYXX CITATION 7QO 8FD FR3 P64 7X8 GPN |
| ID | FETCH-LOGICAL-c499t-1ed4359d879263c71d928a32e2ae92f700474db49795075b0ca5d8f4438ee0983 |
| IEDL.DBID | DOA |
| ISSN | 0100-879X 1414-431X |
| IngestDate | Thu Jul 04 21:01:39 EDT 2024 Wed Sep 25 03:33:54 EDT 2024 Wed Jul 24 12:25:36 EDT 2024 Fri Aug 16 09:41:03 EDT 2024 Fri Aug 23 03:45:23 EDT 2024 Sat Sep 28 08:37:03 EDT 2024 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 6 |
| Keywords | Cardiopulmonary bypass Coronary artery bypass graft Hypoxemia Computed tomography |
| Language | English Portuguese |
| License | This work is licensed under a Creative Commons Attribution 4.0 International License. http://creativecommons.org/licenses/by/4.0 |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c499t-1ed4359d879263c71d928a32e2ae92f700474db49795075b0ca5d8f4438ee0983 |
| Notes | ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 ObjectType-Article-1 ObjectType-Feature-2 |
| OpenAccessLink | https://doaj.org/article/80380ec96afd4b3ebddee3fc066b2705 |
| PMID | 21519640 |
| PQID | 1439217280 |
| PQPubID | 23462 |
| PageCount | 8 |
| ParticipantIDs | doaj_primary_oai_doaj_org_article_80380ec96afd4b3ebddee3fc066b2705 scielo_journals_S0100_879X2011000600014 proquest_miscellaneous_871968640 proquest_miscellaneous_1439217280 crossref_primary_10_1590_S0100_879X2011007500048 pubmed_primary_21519640 |
| PublicationCentury | 2000 |
| PublicationDate | 2011-Jun 2011-06-00 20110601 2011-06-01 |
| PublicationDateYYYYMMDD | 2011-06-01 |
| PublicationDate_xml | – month: 06 year: 2011 text: 2011-Jun |
| PublicationDecade | 2010 |
| PublicationPlace | Brazil |
| PublicationPlace_xml | – name: Brazil |
| PublicationTitle | Brazilian journal of medical and biological research |
| PublicationTitleAlternate | Braz J Med Biol Res |
| PublicationYear | 2011 |
| Publisher | Associação Brasileira de Divulgação Científica |
| Publisher_xml | – name: Associação Brasileira de Divulgação Científica |
| References | Kjaergaard S (ref14) 2004; 21 Kolff WJ (ref1) 1958; 25 Massoudy P (ref17) 2001; 119 Boldt J (ref20) 1991; 5 Tenling A (ref10) 1998; 89 Malbouisson LM (ref21) 2001; 27 Asimakopoulos G (ref2) 1999; 68 Szeles TF (ref3) 2008; 58 Auler-Junior JO (ref5) 1986; 19 Massoudy P (ref16) 1999; 4 Magnusson L (ref4) 1997; 87 Vieira SR (ref13) 1998; 158 Vargas FS (ref6) 1993; 104 Nozawa E (ref8) 2003; 80 Pelosi P (ref22) 1994; 149 Hachenberg T (ref9) 1992; 36 de Vroege R (ref15) 1997; 12 Massoudy P (ref19) 2003; 76 Vargas FS (ref7) 1997; 91 Schlensak C (ref18) 2000; 48 Puybasset L (ref12) 1998; 158 Hedenstierna G (ref11) 1994; 49 Massoudy, P; Zahler, S; Becker, BF; Braun, SL; Barankay, A; Meisner, H 2001; 119 Vargas, FS; Terra-Filho, M; Hueb, W; Teixeira, LR; Cukier, A; Light, RW 1997; 91 Schlensak, C; Doenst, T; Spillner, G; Blum, U; Geiger, A; Beyersdorf, F 2000; 48 Asimakopoulos, G; Smith, PL; Ratnatunga, CP; Taylor, KM 1999; 68 Auler-Junior, JO; Saldiva, PH 1986; 19 Massoudy, P; Piotrowski, JA; van, de Wal HC; Giebler, R; Marggraf, G; Peters, J 2003; 76 Kolff, WJ; Effler, DB; Groves, LK; Hughes, CR; McCormack, LJ 1958; 25 Tenling, A; Hachenberg, T; Tyden, H; Wegenius, G; Hedenstierna, G 1998; 89 Szeles, TF; Yoshinaga, EM; Alenca, W; Brudniewski, M; Ferreira, FS; Auler, JO 2008; 58 Magnusson, L; Zemgulis, V; Wicky, S; Tyden, H; Thelin, S; Hedenstierna, G 1997; 87 de, Vroege R; Rutten, PM; Kalkman, C; Out, TA; Jansen, PG; Eijsman, L 1997; 12 Nozawa, E; Kobayashi, E; Matsumoto, ME; Feltrim, MI; Carmona, MJ; Auler, JJ 2003; 80 Malbouisson, LM; Preteux, F; Puybasset, L; Grenier, P; Coriat, P; Rouby, JJ 2001; 27 Hachenberg, T; Brussel, T; Roos, N; Lenzen, H; Mollhoff, T; Gockel, B 1992; 36 Massoudy, P; Zahler, S; Becker, BF; Braun, SL; Barankay, A; Richter, JA 1999; 4 Hedenstierna, G 1994; 49 Kjaergaard, S; Rees, SE; Gronlund, J; Nielsen, EM; Lambert, P; Thorgaard, P 2004; 21 Vargas, FS; Cukier, A; Terra-Filho, M; Hueb, W; Teixeira, LR; Light, RW 1993; 104 Puybasset, L; Cluzel, P; Chao, N; Slutsky, AS; Coriat, P; Rouby, JJ 1998; 158 Boldt, J; Zickmann, B; Dapper, F; Hempelmann, G 1991; 5 Pelosi, P; D'Andrea, L; Vitale, G; Pesenti, A; Gattinoni, L 1994; 149 Vieira, SR; Puybasset, L; Richecoeur, J; Lu, Q; Cluzel, P; Gusman, PB 1998; 158 |
| References_xml | – volume: 25 start-page: 65 issn: 0009-8787 year: 1958 ident: ref1 article-title: Pulmonary complications of open-heart operations: their pathogenesis and avoidance publication-title: Cleve Clin Q doi: 10.3949/ccjm.25.2.65 contributor: fullname: Kolff WJ – volume: 4 start-page: 178 issn: 0949-2321 year: 1999 ident: ref16 article-title: Significant leukocyte and platelet retention during pulmonary passage after declamping of the aorta in CABG patients publication-title: Eur J Med Res contributor: fullname: Massoudy P – volume: 76 start-page: 516 issn: 0003-4975 year: 2003 ident: ref19 article-title: Perfusing and ventilating the patient's lungs during bypass ameliorates the increase in extravascular thermal volume after coronary bypass grafting publication-title: Ann Thorac Surg doi: 10.1016/S0003-4975(03)00347-3 contributor: fullname: Massoudy P – volume: 158 start-page: 1571 issn: 1073-449X year: 1998 ident: ref13 article-title: A lung computed tomographic assessment of positive end-expiratory pressure-induced lung overdistension publication-title: Am J Respir Crit Care Med doi: 10.1164/ajrccm.158.5.9802101 contributor: fullname: Vieira SR – volume: 21 start-page: 296 issn: 0265-0215 year: 2004 ident: ref14 article-title: Hypoxaemia after cardiac surgery: clinical application of a model of pulmonary gas exchange publication-title: Eur J Anaesthesiol doi: 10.1097/00003643-200404000-00008 contributor: fullname: Kjaergaard S – volume: 87 start-page: 1153 issn: 0003-3022 year: 1997 ident: ref4 article-title: Atelectasis is a major cause of hypoxemia and shunt after cardiopulmonary bypass: an experimental study publication-title: Anesthesiology doi: 10.1097/00000542-199711000-00020 contributor: fullname: Magnusson L – volume: 58 start-page: 124 issn: 0034-7094 year: 2008 ident: ref3 article-title: Hypoxemia after myocardial revascularization: analysis of risk factors publication-title: Rev Bras Anestesiol contributor: fullname: Szeles TF – volume: 158 start-page: 1644 issn: 1073-449X year: 1998 ident: ref12 article-title: A computed tomography scan assessment of regional lung volume in acute lung injury: The CT Scan ARDS Study Group publication-title: Am J Respir Crit Care Med doi: 10.1164/ajrccm.158.5.9802003 contributor: fullname: Puybasset L – volume: 5 start-page: 22 issn: 1010-7940 year: 1991 ident: ref20 article-title: Does the technique of cardiopulmonary bypass affect lung water content? publication-title: Eur J Cardiothorac Surg doi: 10.1016/1010-7940(91)90078-X contributor: fullname: Boldt J – volume: 49 start-page: 315 issn: 1122-0643 year: 1994 ident: ref11 article-title: Atelectasis formation and gas exchange impairment during anaesthesia publication-title: Monaldi Arch Chest Dis contributor: fullname: Hedenstierna G – volume: 12 start-page: 369 issn: 0267-6591 year: 1997 ident: ref15 article-title: Biocompatibility of three different membrane oxygenators: effects on complement, neutrophil and monocyte activation publication-title: Perfusion doi: 10.1177/026765919701200605 contributor: fullname: de Vroege R – volume: 48 start-page: 41 issn: 0171-6425 year: 2000 ident: ref18 article-title: Palliative treatment of a secondary aortoduodenal fistula by stent-graft placement publication-title: Thorac Cardiovasc Surg doi: 10.1055/s-2000-8896 contributor: fullname: Schlensak C – volume: 36 start-page: 800 issn: 0001-5172 year: 1992 ident: ref9 article-title: Gas exchange impairment and pulmonary densities after cardiac surgery publication-title: Acta Anaesthesiol Scand doi: 10.1111/j.1399-6576.1992.tb03568.x contributor: fullname: Hachenberg T – volume: 27 start-page: 602 issn: 0342-4642 year: 2001 ident: ref21 article-title: Validation of a software designed for computed tomographic (CT) measurement of lung water publication-title: Intensive Care Med doi: 10.1007/s001340100860 contributor: fullname: Malbouisson LM – volume: 19 start-page: 707 issn: 0100-879X year: 1986 ident: ref5 article-title: Pulmonary structure and extravascular lung water after cardiopulmonary bypass publication-title: Braz J Med Biol Res contributor: fullname: Auler-Junior JO – volume: 91 start-page: 629 issn: 0954-6111 year: 1997 ident: ref7 article-title: Pulmonary function after coronary artery bypass surgery publication-title: Respir Med doi: 10.1016/S0954-6111(97)90010-X contributor: fullname: Vargas FS – volume: 89 start-page: 371 issn: 0003-3022 year: 1998 ident: ref10 article-title: Atelectasis and gas exchange after cardiac surgery publication-title: Anesthesiology doi: 10.1097/00000542-199808000-00013 contributor: fullname: Tenling A – volume: 80 start-page: 301 issn: 0066-782X year: 2003 ident: ref8 article-title: Assessment of factors that influence weaning from long-term mechanical ventilation after cardiac surgery publication-title: Arq Bras Cardiol doi: 10.1590/S0066-782X2003000300006 contributor: fullname: Nozawa E – volume: 119 start-page: 31 issn: 0012-3692 year: 2001 ident: ref17 article-title: Evidence for inflammatory responses of the lungs during coronary artery bypass grafting with cardiopulmonary bypass publication-title: Chest doi: 10.1378/chest.119.1.31 contributor: fullname: Massoudy P – volume: 149 start-page: 8 issn: 1073-449X year: 1994 ident: ref22 article-title: Vertical gradient of regional lung inflation in adult respiratory distress syndrome publication-title: Am J Respir Crit Care Med doi: 10.1164/ajrccm.149.1.8111603 contributor: fullname: Pelosi P – volume: 68 start-page: 1107 issn: 0003-4975 year: 1999 ident: ref2 article-title: Lung injury and acute respiratory distress syndrome after cardiopulmonary bypass publication-title: Ann Thorac Surg doi: 10.1016/S0003-4975(99)00781-X contributor: fullname: Asimakopoulos G – volume: 104 start-page: 434 issn: 0012-3692 year: 1993 ident: ref6 article-title: Influence of atelectasis on pulmonary function after coronary artery bypass grafting publication-title: Chest doi: 10.1378/chest.104.2.434 contributor: fullname: Vargas FS – volume: 89 start-page: 371 year: 1998 end-page: 378 article-title: Atelectasis and gas exchange after cardiac surgery publication-title: Anesthesiology contributor: fullname: Tenling, A; Hachenberg, T; Tyden, H; Wegenius, G; Hedenstierna, G – volume: 76 start-page: 516 year: 2003 end-page: 521 article-title: Perfusing and ventilating the patient's lungs during bypass ameliorates the increase in extravascular thermal volume after coronary bypass grafting publication-title: Ann Thorac Surg contributor: fullname: Massoudy, P; Piotrowski, JA; van, de Wal HC; Giebler, R; Marggraf, G; Peters, J – volume: 149 start-page: 8 year: 1994 end-page: 13 article-title: Vertical gradient of regional lung inflation in adult respiratory distress syndrome publication-title: Am J Respir Crit Care Med contributor: fullname: Pelosi, P; D'Andrea, L; Vitale, G; Pesenti, A; Gattinoni, L – volume: 58 start-page: 124 year: 2008 end-page: 136 article-title: Hypoxemia after myocardial revascularization: analysis of risk factors publication-title: Rev Bras Anestesiol contributor: fullname: Szeles, TF; Yoshinaga, EM; Alenca, W; Brudniewski, M; Ferreira, FS; Auler, JO – volume: 27 start-page: 602 year: 2001 end-page: 608 article-title: Validation of a software designed for computed tomographic (CT) measurement of lung water publication-title: Intensive Care Med contributor: fullname: Malbouisson, LM; Preteux, F; Puybasset, L; Grenier, P; Coriat, P; Rouby, JJ – volume: 104 start-page: 434 year: 1993 end-page: 437 article-title: Influence of atelectasis on pulmonary function after coronary artery bypass grafting publication-title: Chest contributor: fullname: Vargas, FS; Cukier, A; Terra-Filho, M; Hueb, W; Teixeira, LR; Light, RW – volume: 48 start-page: 41 year: 2000 end-page: 42 article-title: Palliative treatment of a secondary aortoduodenal fistula by stent-graft placement publication-title: Thorac Cardiovasc Surg contributor: fullname: Schlensak, C; Doenst, T; Spillner, G; Blum, U; Geiger, A; Beyersdorf, F – volume: 5 start-page: 22 year: 1991 end-page: 26 article-title: Does the technique of cardiopulmonary bypass affect lung water content? publication-title: Eur J Cardiothorac Surg contributor: fullname: Boldt, J; Zickmann, B; Dapper, F; Hempelmann, G – volume: 49 start-page: 315 year: 1994 end-page: 322 article-title: Atelectasis formation and gas exchange impairment during anaesthesia publication-title: Monaldi Arch Chest Dis contributor: fullname: Hedenstierna, G – volume: 12 start-page: 369 year: 1997 end-page: 375 article-title: Biocompatibility of three different membrane oxygenators: effects on complement, neutrophil and monocyte activation publication-title: Perfusion contributor: fullname: de, Vroege R; Rutten, PM; Kalkman, C; Out, TA; Jansen, PG; Eijsman, L – volume: 4 start-page: 178 year: 1999 end-page: 182 article-title: Significant leukocyte and platelet retention during pulmonary passage after declamping of the aorta in CABG patients publication-title: Eur J Med Res contributor: fullname: Massoudy, P; Zahler, S; Becker, BF; Braun, SL; Barankay, A; Richter, JA – volume: 80 start-page: 301 year: 2003 end-page: 310 article-title: Assessment of factors that influence weaning from long-term mechanical ventilation after cardiac surgery publication-title: Arq Bras Cardiol contributor: fullname: Nozawa, E; Kobayashi, E; Matsumoto, ME; Feltrim, MI; Carmona, MJ; Auler, JJ – volume: 36 start-page: 800 year: 1992 end-page: 805 article-title: Gas exchange impairment and pulmonary densities after cardiac surgery publication-title: Acta Anaesthesiol Scand contributor: fullname: Hachenberg, T; Brussel, T; Roos, N; Lenzen, H; Mollhoff, T; Gockel, B – volume: 158 start-page: 1644 year: 1998 end-page: 1655 article-title: A computed tomography scan assessment of regional lung volume in acute lung injury: The CT Scan ARDS Study Group publication-title: Am J Respir Crit Care Med contributor: fullname: Puybasset, L; Cluzel, P; Chao, N; Slutsky, AS; Coriat, P; Rouby, JJ – volume: 87 start-page: 1153 year: 1997 end-page: 1163 article-title: Atelectasis is a major cause of hypoxemia and shunt after cardiopulmonary bypass: an experimental study publication-title: Anesthesiology contributor: fullname: Magnusson, L; Zemgulis, V; Wicky, S; Tyden, H; Thelin, S; Hedenstierna, G – volume: 158 start-page: 1571 year: 1998 end-page: 1577 article-title: A lung computed tomographic assessment of positive end-expiratory pressure-induced lung overdistension publication-title: Am J Respir Crit Care Med contributor: fullname: Vieira, SR; Puybasset, L; Richecoeur, J; Lu, Q; Cluzel, P; Gusman, PB – volume: 25 start-page: 65 year: 1958 end-page: 83 article-title: Pulmonary complications of open-heart operations: their pathogenesis and avoidance publication-title: Cleve Clin Q contributor: fullname: Kolff, WJ; Effler, DB; Groves, LK; Hughes, CR; McCormack, LJ – volume: 68 start-page: 1107 year: 1999 end-page: 1115 article-title: Lung injury and acute respiratory distress syndrome after cardiopulmonary bypass publication-title: Ann Thorac Surg contributor: fullname: Asimakopoulos, G; Smith, PL; Ratnatunga, CP; Taylor, KM – volume: 91 start-page: 629 year: 1997 end-page: 633 article-title: Pulmonary function after coronary artery bypass surgery publication-title: Respir Med contributor: fullname: Vargas, FS; Terra-Filho, M; Hueb, W; Teixeira, LR; Cukier, A; Light, RW – volume: 21 start-page: 296 year: 2004 end-page: 301 article-title: Hypoxaemia after cardiac surgery: clinical application of a model of pulmonary gas exchange publication-title: Eur J Anaesthesiol contributor: fullname: Kjaergaard, S; Rees, SE; Gronlund, J; Nielsen, EM; Lambert, P; Thorgaard, P – volume: 19 start-page: 707 year: 1986 end-page: 714 article-title: Pulmonary structure and extravascular lung water after cardiopulmonary bypass publication-title: Braz J Med Biol Res contributor: fullname: Auler-Junior, JO; Saldiva, PH – volume: 119 start-page: 31 year: 2001 end-page: 36 article-title: Evidence for inflammatory responses of the lungs during coronary artery bypass grafting with cardiopulmonary bypass publication-title: Chest contributor: fullname: Massoudy, P; Zahler, S; Becker, BF; Braun, SL; Barankay, A; Meisner, H |
| SSID | ssj0025041 |
| Score | 2.0738592 |
| Snippet | Hypoxemia is a frequent complication after coronary artery bypass graft (CABG) with cardiopulmonary bypass (CPB), usually attributed to atelectasis. Using... |
| SourceID | doaj scielo proquest crossref pubmed |
| SourceType | Open Website Open Access Repository Aggregation Database Index Database |
| StartPage | 598 |
| SubjectTerms | Aged Aged, 80 and over Analysis of Variance Apnea - diagnostic imaging Apnea - etiology BIOLOGY Body Water Cardiac Surgical Procedures - adverse effects Cardiopulmonary bypass Cardiopulmonary Bypass - adverse effects Computed tomography Coronary artery bypass graft Female Humans Hypoxemia Lung - diagnostic imaging Male MEDICINE, RESEARCH & EXPERIMENTAL Middle Aged Pulmonary Atelectasis - complications Tomography, X-Ray Computed |
| Title | Computed tomography assessment of lung structure in patients undergoing cardiac surgery with cardiopulmonary bypass |
| URI | https://www.ncbi.nlm.nih.gov/pubmed/21519640 https://search.proquest.com/docview/1439217280 https://search.proquest.com/docview/871968640 http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011000600014&lng=en&tlng=en https://doaj.org/article/80380ec96afd4b3ebddee3fc066b2705 |
| Volume | 44 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1NS8QwFAziQbyI365fRBA8FdM2aZOjiiKCXlTYW2nSVARtxa4H_72Tj10UFS9es-lumzdv30zaziPkEJoBcRZpUuuMJxyUPVHMOCNIKUqD-iO9l971TXF5z6_GYvyp1Zd7JizYA4eFO5Ysl8waVdRtw3VuNfLR5q1BqdRZGd1LUzEVU1FqCeZ7Vqb48QQlchyf7BKKHd9CgTD8Caixr32uZDoYf6lL3r7_J87pDEWRc0-fi9DFMlmK7JGehLNeIXO2WyUL1_H--BoZYpOGhk7652hGTeuZ-SbtW_qE7KbBNfbt1dLHjkZr1YG698leH3oUM2o8cAwdwlvT1G3XhkHX8AvQrTGo31_w3evk_uL87uwyiW0VEgN5M0lS24AjqQZLkBW5KdNGZbLOM5vVVmWt87sveaO5KhXIotDM1KKRLee5tJYpmW-Q-a7v7BahxpSosUaJBszP5FqXIDRKZprrEocXI8Kmi1q9BPeMyqkOxKHycai-xWFETt3iz6Y7-2s_AFBUERTVX6AYkYNp6Cqki7sHUne2fxugdEAIfU-uEaG_zIGGBFQLjimbIeyzs3EESflPjgIOqpjyw7frYYXXn9v_cT07ZDHsZbvdn10yD5DYPZChid73uP8AgRMBoQ |
| link.rule.ids | 230,315,786,790,870,891,2115,27957,27958 |
| linkProvider | Directory of Open Access Journals |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Computed+tomography+assessment+of+lung+structure+in+patients+undergoing+cardiac+surgery+with+cardiopulmonary+bypass&rft.jtitle=Brazilian+journal+of+medical+and+biological+research&rft.au=Rodrigues%2C+R+R&rft.au=Sawada%2C+A+Y&rft.au=Rouby%2C+J-J&rft.au=Fukuda%2C+M+J&rft.date=2011-06-01&rft.eissn=1414-431X&rft.volume=44&rft.issue=6&rft.spage=598&rft_id=info:doi/10.1590%2FS0100-879X2011007500048&rft_id=info%3Apmid%2F21519640&rft.externalDocID=21519640 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0100-879X&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0100-879X&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0100-879X&client=summon |