Helminth parasites - masters of regulation

• Published in: Immunological reviews Vol. 201; no. 1; pp. 89 - 116
• Main Authors: Maizels, Rick M., Balic, Adam, Gomez-Escobar, Natalia, Nair, Meera, Taylor, Matt D., Allen, Judith E.
• Format: Journal Article
• Language: English
• Published: Oxford, UK; Malden, USA Munksgaard International Publishers 01.10.2004
• Subjects: Animals; Disease Models, Animal; Gene Expression Regulation; Helminthiasis - immunology; Helminthiasis - parasitology; Helminthiasis - physiopathology; Helminths - immunology; Helminths - pathogenicity; Host-Parasite Interactions; Humans; Immunity; Mice; Mice, Inbred Strains; Platyhelminthes

Immune regulation by parasites is a global concept that includes suppression, diversion, and conversion of the host immune response to the benefit of the pathogen. While many microparasites escape immune attack by antigenic variation or sequestration in specialized niches, helminths appear to thrive...