Reduction of auditory event-related P300 amplitude in subjects with at-risk mental state for schizophrenia

• Published in: Schizophrenia research Vol. 105; no. 1; pp. 272 - 278
• Main Authors: Özgürdal, Seza, Gudlowski, Yehonala, Witthaus, Henning, Kawohl, Wolfram, Uhl, Idun, Hauser, Marta, Gorynia, Inge, Gallinat, Jürgen, Heinze, Martin, Heinz, Andreas, Juckel, Georg
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier B.V 01.10.2008; Elsevier Science
• Subjects: Acoustic Stimulation; Adult; Adult and adolescent clinical studies; Attention; Auditory evoked P300; Auditory oddball paradigm; Biological and medical sciences; Brain Mapping; Cognition; Cognition Disorders - diagnosis; Cognition Disorders - physiopathology; Control Groups; Cross-Sectional Studies; Electroencephalography - statistics & numerical data; Event-related potentials; Event-Related Potentials, P300 - physiology; Evoked Potentials, Auditory - physiology; Female; Humans; Male; Medical sciences; Neurophysiological changes; Neuropsychological Tests; Prodromal patients; Psychiatric Status Rating Scales; Psychiatric/Mental Health; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Psychoses; Risk Factors; Schizophrenia; Schizophrenia - diagnosis; Schizophrenia - physiopathology; Schizophrenic Psychology; Neurophysiological changes; Auditory oddball paradigm; Auditory evoked P300; Schizophrenia; Prodromal patients; Event-related potentials; Cognition; Human; High risk; Central nervous system; Electrophysiology; P300 potential; Experimental study; Encephalon; Neurophysiology; Psychosis; Hearing; First episode; Auditory evoked potential; Perception; Event evoked potential; Prepsychotic state; Comparative study

Neurophysiological methods allow the examination of cognitive–cortical functioning in patients with schizophrenia in its prodromal states. As revealed by previous studies, event-related potential components such as auditory evoked P300 associated with cognitive processes, such as attention and orien...