Cancer theory faces doubts
OSI Pharmaceuticals, based in Melville, New York, is already pursuing EMT inhibitors as possible cancer treatments, as are several academic labs. "EMT is really becoming a popular subject," says Shoukat Dedhar, a cancer researcher at the British Columbia Cancer Research Centre in Vancouver...
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| Published in | Nature (London) Vol. 472; no. 7343; p. 273 |
|---|---|
| Main Author | |
| Format | Journal Article |
| Language | English |
| Published |
London
Nature Publishing Group UK
21.04.2011
Nature Publishing Group |
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| Online Access | Get full text |
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| Abstract | OSI Pharmaceuticals, based in Melville, New York, is already pursuing EMT inhibitors as possible cancer treatments, as are several academic labs. "EMT is really becoming a popular subject," says Shoukat Dedhar, a cancer researcher at the British Columbia Cancer Research Centre in Vancouver and a self-avowed convert to the hypothesis. CONFLICTING IDEAS Champions of the EMT-metastasis hypothesis, including leading cancer biologist Robert Weinberg at the Whitehead Institute for Biomedical Research in Cambridge, Massachusetts, say that this may simply be because EMT is so transient - once a metastatic cell has invaded a new tissue, its mesenchymal features melt away. |
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| AbstractList | OSI Pharmaceuticals, based in Melville, New York, is already pursuing EMT inhibitors as possible cancer treatments, as are several academic labs. "EMT is really becoming a popular subject," says Shoukat Dedhar, a cancer researcher at the British Columbia Cancer Research Centre in Vancouver and a self-avowed convert to the hypothesis. CONFLICTING IDEAS Champions of the EMT-metastasis hypothesis, including leading cancer biologist Robert Weinberg at the Whitehead Institute for Biomedical Research in Cambridge, Massachusetts, say that this may simply be because EMT is so transient - once a metastatic cell has invaded a new tissue, its mesenchymal features melt away. A leading explanation for how disease migrates falls short on clinical evidence. |
| Audience | Academic |
| Author | Ledford, Heidi |
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| Copyright | Springer Nature Limited 2011 COPYRIGHT 2011 Nature Publishing Group Copyright Nature Publishing Group Apr 21, 2011 |
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| Snippet | A leading explanation for how disease migrates falls short on clinical evidence. OSI Pharmaceuticals, based in Melville, New York, is already pursuing EMT inhibitors as possible cancer treatments, as are several academic labs. "EMT is... |
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| Title | Cancer theory faces doubts |
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