A novel method for engineering autologous non-thrombogenic in situ tissue-engineered blood vessels for arteriovenous grafting

• Published in: Biomaterials Vol. 229; p. 119577
• Main Authors: Geelhoed, W.J., van der Bogt, K.E.A., Rothuizen, T.C., Damanik, F.F.R., Hamming, J.F., Mota, C.D., van Agen, M.S., de Boer, H.C., Restrepo, M. Tobón, Hinz, B., Kislaya, A., Poelma, C., van Zonneveld, A.J., Rabelink, T.J., Moroni, L., Rotmans, J.I.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 01.01.2020
• Subjects: Blood Vessel Prosthesis; Blood Vessel Prosthesis Implantation; Carotid Arteries - surgery; Jugular Veins - surgery; Renal Dialysis; Tissue Engineering; Vascular Patency

The durability of prosthetic arteriovenous (AV) grafts for hemodialysis access is low, predominantly due to stenotic lesions in the venous outflow tract and infectious complications. Tissue engineered blood vessels (TEBVs) might offer a tailor-made autologous alternative for prosthetic grafts. We ha...