Abnormal proprioceptive-motor integration contributes to hypometric postural responses of subjects with parkinson’s disease

• Published in: Neuroscience Vol. 141; no. 2; pp. 999 - 1009
• Main Authors: Jacobs, J.V., Horak, F.B.
• Format: Journal Article
• Language: English
• Published: Oxford Elsevier Ltd 01.01.2006; Elsevier
• Subjects: Aged; balance; Biological and medical sciences; Biomechanical Phenomena; Case-Control Studies; Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases; Eye and associated structures. Visual pathways and centers. Vision; Female; Functional Laterality - physiology; Fundamental and applied biological sciences. Psychology; Humans; kinesthesia; Male; Medical sciences; Middle Aged; Movement - physiology; Neurology; Parkinson Disease - physiopathology; Postural Balance - physiology; posture; Posture - physiology; proprioception; Proprioception - physiology; Psychomotor Performance - physiology; Vertebrates: nervous system and sense organs; vision; vision; balance; kinesthesia; PD; ANOVA; posture; SMA; UPDRS; proprioception; dlPMC; AP; ML; Human; Nervous system diseases; Proprioception; Vision; Central nervous system disease; Parkinson disease; Degenerative disease; Kinesthesia; Cerebral disorder; Extrapyramidal syndrome; Posture

Subjects with Parkinson’s disease exhibit abnormally short compensatory steps in response to external postural perturbations. We examined whether: (1) Parkinson’s disease subjects exhibit short compensatory steps due to abnormal central proprioceptive-motor integration, (2) this proprioceptive-motor...