Association of peroxisome proliferator-activated receptor delta and additional gene-smoking interaction on cardiovascular disease

• Published in: Clinical and experimental hypertension (1993) Vol. 39; no. 2; pp. 114 - 118
• Main Authors: Yang, Wenqi, Mao, Shudan, Qu, Baoze, Zhang, Fengxiang, Xu, Zhaolong
• Format: Journal Article
• Language: English
• Published: England Taylor & Francis 17.02.2017; Taylor & Francis Group
• Subjects: Adult; Aged; Alleles; Asian Continental Ancestry Group - genetics; Asian Continental Ancestry Group - statistics & numerical data; Cardiovascular disease; Cardiovascular Diseases - epidemiology; Cardiovascular Diseases - genetics; China - epidemiology; Female; Gene-Environment Interaction; Genotype; Heterozygote; Humans; interaction; Logistic Models; Male; Middle Aged; Odds Ratio; polymorphism; Polymorphism, Single Nucleotide; PPAR delta - genetics; PPAR-δ; smoking; Smoking - epidemiology; interaction; PPAR-δ; Cardiovascular disease; polymorphism; smoking

Aims: To investigate the impact of peroxisome proliferator-activator receptor delta (PPARD) gene polymorphism and additional gene-smoking interaction on cardiovascular disease (CVD) risk based on this Chinese population. Methods: A total of 1048 subjects (617 males, 431 females) with a mean age of 5...