The Blalock-Taussig Shunt Revisited: A Contemporary Experience
Background The Blalock-Taussig shunt (BTS) was introduced 68 years ago before open repair of cyanotic congenital heart disease (CHD) was possible. The originally described technique has undergone many modifications but remains an integral component of the management of cyanotic CHD. We report our co...
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Published in | Journal of the American College of Surgeons Vol. 216; no. 4; pp. 699 - 704 |
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Main Authors | , , , , , , , |
Format | Journal Article |
Language | English |
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Elsevier Inc
01.04.2013
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Abstract | Background The Blalock-Taussig shunt (BTS) was introduced 68 years ago before open repair of cyanotic congenital heart disease (CHD) was possible. The originally described technique has undergone many modifications but remains an integral component of the management of cyanotic CHD. We report our contemporary, single institution experience with the BTS. Study Design We performed a retrospective review of all patients treated with a BTS from June 1995 to December 2011. Results There were 730 BTS performed in 712 patients; 727 (99.6%) by interposition graft (modified). The BTS was predominantly right-sided (n = 657, 90%). Median age and weight at palliation were 8 days (range 0 days to 18.5 years) and 3.2 kg (1.5 to 51 kg). Median hospital length of stay was 16 days (range 0 to 347 days). There were 241 (33%) BTS performed as initial palliation for ultimate 2-ventricle (2V) circulation, 471 (65%) as part of staged palliation for patients with functionally univentricular lesions (1V), 6 (1%) as a part of 1.5-ventricle palliation, and 12 (1%) for Ebstein's anomaly. There were 473 (65%) BTS placed via sternotomy and the most common site of BTS was the right subclavian to right pulmonary artery (PA; n = 452, 62%). Hospital mortality was higher for BTS in 1V patients (1V 15% vs 2V 3%, p < 0.0001). Overall, 536 (73%) patients were bridged to complete repair or the second stage of 1V palliation after a median duration of 6.5 months (0 days to 15.3 years). Multivariable regression showed that sternotomy approach, use of cardiopulmonary bypass, innominate artery-PA shunt, and diagnosis of Ebstein's were risk factors for in-hospital mortality (p < 0.05). Conclusions Although the BTS remains an important component of the surgical treatment of cyanotic congenital heart disease, patients with single ventricle circulation still face significant ongoing risk of mortality. |
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AbstractList | Background The Blalock-Taussig shunt (BTS) was introduced 68 years ago before open repair of cyanotic congenital heart disease (CHD) was possible. The originally described technique has undergone many modifications but remains an integral component of the management of cyanotic CHD. We report our contemporary, single institution experience with the BTS. Study Design We performed a retrospective review of all patients treated with a BTS from June 1995 to December 2011. Results There were 730 BTS performed in 712 patients; 727 (99.6%) by interposition graft (modified). The BTS was predominantly right-sided (n = 657, 90%). Median age and weight at palliation were 8 days (range 0 days to 18.5 years) and 3.2 kg (1.5 to 51 kg). Median hospital length of stay was 16 days (range 0 to 347 days). There were 241 (33%) BTS performed as initial palliation for ultimate 2-ventricle (2V) circulation, 471 (65%) as part of staged palliation for patients with functionally univentricular lesions (1V), 6 (1%) as a part of 1.5-ventricle palliation, and 12 (1%) for Ebstein's anomaly. There were 473 (65%) BTS placed via sternotomy and the most common site of BTS was the right subclavian to right pulmonary artery (PA; n = 452, 62%). Hospital mortality was higher for BTS in 1V patients (1V 15% vs 2V 3%, p < 0.0001). Overall, 536 (73%) patients were bridged to complete repair or the second stage of 1V palliation after a median duration of 6.5 months (0 days to 15.3 years). Multivariable regression showed that sternotomy approach, use of cardiopulmonary bypass, innominate artery-PA shunt, and diagnosis of Ebstein's were risk factors for in-hospital mortality (p < 0.05). Conclusions Although the BTS remains an important component of the surgical treatment of cyanotic congenital heart disease, patients with single ventricle circulation still face significant ongoing risk of mortality. The Blalock-Taussig shunt (BTS) was introduced 68 years ago before open repair of cyanotic congenital heart disease (CHD) was possible. The originally described technique has undergone many modifications but remains an integral component of the management of cyanotic CHD. We report our contemporary, single institution experience with the BTS. We performed a retrospective review of all patients treated with a BTS from June 1995 to December 2011. There were 730 BTS performed in 712 patients; 727 (99.6%) by interposition graft (modified). The BTS was predominantly right-sided (n = 657, 90%). Median age and weight at palliation were 8 days (range 0 days to 18.5 years) and 3.2 kg (1.5 to 51 kg). Median hospital length of stay was 16 days (range 0 to 347 days). There were 241 (33%) BTS performed as initial palliation for ultimate 2-ventricle (2V) circulation, 471 (65%) as part of staged palliation for patients with functionally univentricular lesions (1V), 6 (1%) as a part of 1.5-ventricle palliation, and 12 (1%) for Ebstein's anomaly. There were 473 (65%) BTS placed via sternotomy and the most common site of BTS was the right subclavian to right pulmonary artery (PA; n = 452, 62%). Hospital mortality was higher for BTS in 1V patients (1V 15% vs 2V 3%, p < 0.0001). Overall, 536 (73%) patients were bridged to complete repair or the second stage of 1V palliation after a median duration of 6.5 months (0 days to 15.3 years). Multivariable regression showed that sternotomy approach, use of cardiopulmonary bypass, innominate artery-PA shunt, and diagnosis of Ebstein's were risk factors for in-hospital mortality (p < 0.05). Although the BTS remains an important component of the surgical treatment of cyanotic congenital heart disease, patients with single ventricle circulation still face significant ongoing risk of mortality. BACKGROUNDThe Blalock-Taussig shunt (BTS) was introduced 68 years ago before open repair of cyanotic congenital heart disease (CHD) was possible. The originally described technique has undergone many modifications but remains an integral component of the management of cyanotic CHD. We report our contemporary, single institution experience with the BTS.STUDY DESIGNWe performed a retrospective review of all patients treated with a BTS from June 1995 to December 2011.RESULTSThere were 730 BTS performed in 712 patients; 727 (99.6%) by interposition graft (modified). The BTS was predominantly right-sided (n = 657, 90%). Median age and weight at palliation were 8 days (range 0 days to 18.5 years) and 3.2 kg (1.5 to 51 kg). Median hospital length of stay was 16 days (range 0 to 347 days). There were 241 (33%) BTS performed as initial palliation for ultimate 2-ventricle (2V) circulation, 471 (65%) as part of staged palliation for patients with functionally univentricular lesions (1V), 6 (1%) as a part of 1.5-ventricle palliation, and 12 (1%) for Ebstein's anomaly. There were 473 (65%) BTS placed via sternotomy and the most common site of BTS was the right subclavian to right pulmonary artery (PA; n = 452, 62%). Hospital mortality was higher for BTS in 1V patients (1V 15% vs 2V 3%, p < 0.0001). Overall, 536 (73%) patients were bridged to complete repair or the second stage of 1V palliation after a median duration of 6.5 months (0 days to 15.3 years). Multivariable regression showed that sternotomy approach, use of cardiopulmonary bypass, innominate artery-PA shunt, and diagnosis of Ebstein's were risk factors for in-hospital mortality (p < 0.05).CONCLUSIONSAlthough the BTS remains an important component of the surgical treatment of cyanotic congenital heart disease, patients with single ventricle circulation still face significant ongoing risk of mortality. The Blalock-Taussig shunt (BTS) was introduced 68 years ago before open repair of cyanotic congenital heart disease (CHD) was possible. The originally described technique has undergone many modifications but remains an integral component of the management of cyanotic CHD. We report our contemporary, single institution experience with the BTS. We performed a retrospective review of all patients treated with a BTS from June 1995 to December 2011. There were 730 BTS performed in 712 patients; 727 (99.6%) by interposition graft (modified). The BTS was predominantly right-sided (n = 657, 90%). Median age and weight at palliation were 8 days (range 0 days to 18.5 years) and 3.2 kg (1.5 to 51 kg). Median hospital length of stay was 16 days (range 0 to 347 days). There were 241 (33%) BTS performed as initial palliation for ultimate 2-ventricle (2V) circulation, 471 (65%) as part of staged palliation for patients with functionally univentricular lesions (1V), 6 (1%) as a part of 1.5-ventricle palliation, and 12 (1%) for Ebstein's anomaly. There were 473 (65%) BTS placed via sternotomy and the most common site of BTS was the right subclavian to right pulmonary artery (PA; n = 452, 62%). Hospital mortality was higher for BTS in 1V patients (1V 15% vs 2V 3%, p < 0.0001). Overall, 536 (73%) patients were bridged to complete repair or the second stage of 1V palliation after a median duration of 6.5 months (0 days to 15.3 years). Multivariable regression showed that sternotomy approach, use of cardiopulmonary bypass, innominate artery-PA shunt, and diagnosis of Ebstein's were risk factors for in-hospital mortality (p < 0.05). Although the BTS remains an important component of the surgical treatment of cyanotic congenital heart disease, patients with single ventricle circulation still face significant ongoing risk of mortality. |
Author | Khan, Muhammad S., MD Vener, Daniel S., BS McKenzie, E. Dean, MD, FACS Santos, Alexia B., MD Heinle, Jeffrey S., MD, FACS Fraser, Charles D., MD, FACS Samayoa, Andres X., MD Ishak, Youstina M., BS |
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Keywords | BTS RPA 2V 2 ventricles 1V single ventricle modified BTS (de Leval shunt) right subclavian artery MBTS right pulmonary artery congenital heart disease RSCA Blalock-Taussig shunt CHD |
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References | Lillehei, Cohen, Warden (bib4) 1955; 142 Blalock (bib7) 1946; 124 Evans (bib6) 2009; 19 Blalock, Taussig (bib1) 1945; 128 Levy, Blalock (bib2) 1939; 8 de Leval, McKay, Jones (bib8) 1981; 81 Shauq, Agarwal, Karunaratne (bib11) 2010; 19 Morales, Zafar, Arrington (bib9) 2008; 86 Alkhulaifi, Lacour-Gayet, Serraf (bib10) 2000; 69 Gibbon (bib5) 1968; 206 Williams, Bansal, Kim (bib3) 2007; 84 |
References_xml | – volume: 206 start-page: 1983 year: 1968 end-page: 1986 ident: bib5 article-title: Development of the artificial heart and lung extracorporeal blood circuit publication-title: JAMA contributor: fullname: Gibbon – volume: 128 start-page: 189 year: 1945 end-page: 202 ident: bib1 article-title: The surgical treatment of malformations of the heart in which there is pulmonary stenosis or pulmonary atresia publication-title: JAMA contributor: fullname: Taussig – volume: 81 start-page: 112 year: 1981 end-page: 119 ident: bib8 article-title: Modified Blalock-Taussig shunt. Use of subclavian artery orifice as flow regulator in prosthetic systemic-pulmonary artery shunts publication-title: J Thorac Cardiovasc Surg contributor: fullname: Jones – volume: 19 start-page: 119 year: 2009 end-page: 128 ident: bib6 article-title: The Blalock-Taussig shunt: the social history of an eponym publication-title: Cardiol Young contributor: fullname: Evans – volume: 19 start-page: 460 year: 2010 end-page: 464 ident: bib11 article-title: Surgical approaches to the Blalock shunt: does approach matter? publication-title: Heart Lung Circ contributor: fullname: Karunaratne – volume: 142 start-page: 418 year: 1955 end-page: 442 ident: bib4 article-title: Direct vision intracardiac surgical correction of the tetralogy of Fallot, pentalogy of Fallot, and pulmonary atresia defects; report of first ten cases publication-title: Ann Surg contributor: fullname: Warden – volume: 8 start-page: 525 year: 1939 ident: bib2 article-title: Experimental observations on the effects of connecting by suture the left main pulmonary artery to the systemic circulation publication-title: J Thoracic Surg contributor: fullname: Blalock – volume: 86 start-page: 897 year: 2008 end-page: 902 ident: bib9 article-title: Repeat sternotomy in congenital heart surgery: no longer a risk factor publication-title: Ann Thorac Surg contributor: fullname: Arrington – volume: 84 start-page: 2070 year: 2007 end-page: 2075 ident: bib3 article-title: Two thousand Blalock-Taussig shunts: a six-decade experience publication-title: Ann Thorac Surg contributor: fullname: Kim – volume: 124 start-page: 879 year: 1946 end-page: 885 ident: bib7 article-title: The surgical treatment of congenital pulmonic stenosis publication-title: Ann Surg contributor: fullname: Blalock – volume: 69 start-page: 1499 year: 2000 end-page: 1504 ident: bib10 article-title: Systemic pulmonary shunts in neonates: early clinical outcome and choice of surgical approach publication-title: Ann Thorac Surg contributor: fullname: Serraf |
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Snippet | Background The Blalock-Taussig shunt (BTS) was introduced 68 years ago before open repair of cyanotic congenital heart disease (CHD) was possible. The... The Blalock-Taussig shunt (BTS) was introduced 68 years ago before open repair of cyanotic congenital heart disease (CHD) was possible. The originally... BACKGROUNDThe Blalock-Taussig shunt (BTS) was introduced 68 years ago before open repair of cyanotic congenital heart disease (CHD) was possible. The... |
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Title | The Blalock-Taussig Shunt Revisited: A Contemporary Experience |
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