Immune inhibitory function of bovine CTLA-4 and the effects of its blockade in IFN-γ production - Watari, Kei; Konnai, Satoru; Maekawa, Naoya; Okagawa, Tomohiro; Suzuki, Yasuhiko; Murata, Shiro; Ohashi, Kazuhiko (BMC veterinary research, 2019)
Keywords: Animals; Antibodies; antigens; B7-1 Antigen; B7-2 Antigen; BLV; Bovine leukemia virus; Cattle; CD80; CD86; Chlorocebus aethiops; chronic diseases; COS Cells; CTLA-4; CTLA-4 Antigen - genetics; CTLA-4 Antigen - metabolism; cytotoxicity; disease progression; dose response; enterotoxins; Gene Expression Regulation - drug effects; Gene Expression Regulation - immunology; IFN-γ; immune response; interferon-gamma; Interferon-gamma - genetics; Interferon-gamma - metabolism; Leukocytes, Mononuclear - drug effects; Leukocytes, Mononuclear - metabolism; monoclonal antibodies; neoplasms; Recombinant Proteins; Staphylococcus; T-lymphocytes; therapeutics; CD86; IFN-γ; CTLA-4; Cattle; BLV; CD80