Elevated basal serum tryptase identifies a multisystem disorder associated with increased TPSAB1 copy number - Lyons, Jonathan J; Yu, Xiaomin; Hughes, Jason D; Le, Quang T; Jamil, Ali; Bai, Yun; Ho, Nancy; Zhao, Ming; Liu, Yihui; O'Connell, Michael P; Trivedi, Neil N; Nelson, Celeste; et al. (Nature genetics, 2016)
Keywords: 631/250/248; 692/699/1670/122; Adolescent; Adult; Aged; Agriculture; Animal Genetics and Genomics; Biomedicine; Cancer Research; Child; Chronic Pain - blood; Chronic Pain - enzymology; Chronic Pain - genetics; Comorbidity; Connective Tissue Diseases - blood; Connective Tissue Diseases - enzymology; Connective Tissue Diseases - genetics; DNA Copy Number Variations - genetics; Dysautonomia, Familial - blood; Dysautonomia, Familial - enzymology; Dysautonomia, Familial - genetics; Female; Gastrointestinal Diseases - blood; Gastrointestinal Diseases - enzymology; Gastrointestinal Diseases - genetics; Gene Function; Genes; Genomes; Genomics; Human Genetics; Humans; Irritable bowel syndrome; letter; Male; Middle Aged; Pruritus - blood; Pruritus - enzymology; Pruritus - genetics; Skin Diseases - blood; Skin Diseases - enzymology; Skin Diseases - genetics; Studies; Tryptases - blood; Tryptases - genetics; Young Adult