Clinical impact of routine follow-up coronary angiography after second- or third-generation drug-eluting stent insertion in clinically stable patients

• Published in: The Korean journal of internal medicine Vol. 30; no. 1; pp. 49 - 55
• Main Authors: Choi, Seonghoon, Mun, Hee-Sun, Kang, Min-Kyung, Cho, Jung Rae, Han, Seong Woo, Lee, Namho
• Format: Journal Article
• Language: English
• Published: Korea (South) The Korean Association of Internal Medicine 01.01.2015; 대한내과학회
• Subjects: Aged; Coronary Angiography; Coronary Artery Bypass; Coronary Artery Disease - diagnostic imaging; Coronary Artery Disease - therapy; Coronary Restenosis - diagnostic imaging; Coronary Restenosis - etiology; Coronary Restenosis - surgery; Coronary Vessels - diagnostic imaging; Disease Progression; Disease-Free Survival; Drug-Eluting Stents; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction - diagnostic imaging; Myocardial Infarction - etiology; Myocardial Infarction - surgery; Original; Patient Selection; Percutaneous Coronary Intervention - adverse effects; Percutaneous Coronary Intervention - instrumentation; Predictive Value of Tests; Proportional Hazards Models; Prosthesis Design; Retrospective Studies; Risk Factors; Time Factors; Treatment Outcome; 내과학; Coronary angiography; Drug-eluting stents; Follow-up
• ISSN: 1226-3303; 2005-6648; 2005-6648
• DOI: 10.3904/kjim.2015.30.1.49

In the bare-metal stent era, routine follow-up coronary angiography (RFU CAG) was used to ensure stent patency. With the advent of drug-eluting stents (DESs) with better safety and efficacy profiles, RFU CAG has been performed less often. There are few data on the clinical impact of RFU CAG after second- or third-generation DES implantation in clinically stable patients with coronary artery disease; the aim of this study was to examine this issue. We analyzed clinical outcomes retrospectively of 259 patients who were event-free at 12-month after stent implantation and did not undergo RFU CAG (clinical follow-up group) and 364 patients who were event-free prior to RFU CAG (angiographic follow-up group). Baseline characteristics were compared between the groups. The Kaplan-Meier estimated total survival and major adverse cardiac event (MACE)-free survival did not differ between the groups (p = 0.100 and p = 0.461, respectively). The cumulative MACE rate was also not different between the groups (hazard ratio, 0.85; 95% confidence interval, 0.35 to 2.02). In the angiographic follow-up group, 8.8% revascularization was seen at RFU CAG. RFU CAG did not affect long-term clinical outcome after second- or third-generation DES implantation in clinically stable patients.