Change of Outcomes in Pediatric Intestinal Failure: Use of Time-Series Analysis to Assess the Evolution of an Intestinal Rehabilitation Program

• Published in: Journal of the American College of Surgeons Vol. 222; no. 6; pp. 1180 - 1188.e3
• Main Authors: Oliveira, Carol, MD, PhD, de Silva, Nicole T., MSc, Stanojevic, Sanja, PhD, Avitzur, Yaron, MD, Bayoumi, Ahmed M., MD, MSc, Ungar, Wendy J., PhD, Hoch, Jeffrey S., PhD, Wales, Paul W., MD, MSc, FACS
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.06.2016
• Subjects: Combined Modality Therapy; Fat Emulsions, Intravenous - therapeutic use; Fatty Acids, Omega-3 - therapeutic use; Female; Follow-Up Studies; Humans; Infant; Infant, Newborn; Linear Models; Male; Multivariate Analysis; Retrospective Studies; Short Bowel Syndrome - mortality; Short Bowel Syndrome - rehabilitation; Surgery; Treatment Outcome; intestinal failure; autoregressive integrative moving average models; IRP; catheter-related bloodstream infections; central venous catheter; IQR; interquartile range; CVC; intestinal rehabilitation program; parenteral nutrition; ARIMA; IF; PN; CRBSI

Background The clinical picture of pediatric intestinal failure has changed over the past 15 years, while effectiveness evolving treatment options remains unclear. This study explored evolution in care and quantified independent effects of new treatment options. Study Design Consecutive patients (n ...