Clinical utility of PCR for common viruses in acute respiratory illness

• Published in: Pediatrics (Evanston) Vol. 133; no. 3; p. e538
• Main Authors: Rhedin, Samuel, Lindstrand, Ann, Rotzén-Östlund, Maria, Tolfvenstam, Thomas, Ohrmalm, Lars, Rinder, Malin Ryd, Zweygberg-Wirgart, Benita, Ortqvist, Ake, Henriques-Normark, Birgitta, Broliden, Kristina, Naucler, Pontus
• Format: Journal Article
• Language: English
• Published: United States 01.03.2014
• Subjects: Acute Disease; Case-Control Studies; Child, Preschool; Female; Humans; Infant; Male; Real-Time Polymerase Chain Reaction - utilization; Respiratory Syncytial Viruses - isolation & purification; Respiratory Tract Infections - diagnosis; Respiratory Tract Infections - genetics; Respiratory Tract Infections - virology; Rhinovirus - isolation & purification; Viral Proteins - isolation & purification; viral infections; case-control study; children; respiratory illness; etiology

Acute respiratory illness (ARI) accounts for a large proportion of all visits to pediatric health facilities. Quantitative real-time polymerase chain reaction (qPCR) analyses allow sensitive detection of viral nucleic acids, but it is not clear to what extent specific viruses contribute to disease b...