Increased plasma serotonin metabolite 5-hydroxyindole acetic acid concentrations are associated with impaired systolic and late diastolic forward flows during cardiac cycle and elevated resistive index at popliteal artery and renal insufficiency in type 2 diabetic patients with microalbuminuria - Takami, Kazuhisa; Takeda, Jun; Suzuki, Eiji; Tajima, Yoshitaka; Saito, Jun; Horikawa, Yukio (Endocrine Journal, 2016)
Keywords: 5-hydroxyindole acetic acid; Aged; Albuminuria - blood; Albuminuria - complications; Albuminuria - physiopathology; Ankle Brachial Index; Blood Flow Velocity; Case-Control Studies; Diabetes Mellitus, Type 2 - blood; Diabetes Mellitus, Type 2 - complications; Diabetes Mellitus, Type 2 - physiopathology; Diabetic Angiopathies - blood; Diabetic Angiopathies - complications; Diabetic Angiopathies - physiopathology; Diabetic Nephropathies - blood; Diabetic Nephropathies - complications; Diabetic Nephropathies - physiopathology; Diastole; Female; Flow components during cardiac cycle; Heart Rate - physiology; Humans; Hydroxyindoleacetic Acid - blood; Lower extremity arterial disease; Male; Middle Aged; Peripheral vascular resistance; Popliteal Artery - physiopathology; Renal insufficiency; Renal Insufficiency - blood; Renal Insufficiency - physiopathology; Serotonin - metabolism; Systole; Vascular Resistance - physiology