Ten-year outcomes of high-dose intensity-modulated radiation therapy for nonmetastatic prostate cancer with unfavorable risk: early initiation of salvage therapy may replace long-term adjuvant androgen deprivation

• Published in: International journal of clinical oncology Vol. 24; no. 10; pp. 1247 - 1255
• Main Authors: Aizawa, Rihito, Takayama, Kenji, Nakamura, Kiyonao, Inoue, Takahiro, Yamasaki, Toshinari, Kobayashi, Takashi, Akamatsu, Shusuke, Ogawa, Osamu, Mizowaki, Takashi
• Format: Journal Article
• Language: English
• Published: Singapore Springer Singapore 01.10.2019; Springer Nature B.V
• Subjects: Androgens; Cancer Research; Medicine; Medicine & Public Health; Morbidity; Oncology; Original; Original Article; Patients; Prostate cancer; Prostate-specific antigen; Radiation therapy; Rectum; Surgical Oncology; Survival; Intensity-modulated radiation therapy; Early salvage androgen deprivation therapy; Short-term androgen deprivation therapy; Prostate cancer; Unfavorable risk

Background The optimal timing of salvage androgen deprivation therapy (ADT) following definitive radiation therapy for prostate cancer (PCa) is unknown. This study evaluated the efficacy of early initiation of salvage-ADT (S-ADT) based on predetermined timing among patients with unfavorable PCa trea...