HBeAg-positive patients with HBsAg  < 100 IU/mL and negative HBV RNA have lower risk of virological relapse after nucleos(t)ide analogues cessation

• Published in: Journal of gastroenterology Vol. 56; no. 9; pp. 856 - 867
• Main Authors: Xie, Yandi, Li, Minghui, Ou, Xiaojuan, Zheng, Sujun, Gao, Yinjie, Xu, Xiaoyuan, Yang, Ying, Ma, Anlin, Li, Jia, Huang, Yuan, Nan, Yuemin, Zheng, Huanwei, Feng, Bo
• Format: Journal Article
• Language: English
• Published: Singapore Springer Singapore 01.09.2021; Springer Nature B.V
• Subjects: Abdominal Surgery; Adult; Antigens; Antiviral Agents - therapeutic use; Biliary Tract; China - epidemiology; Cohort Studies; Colorectal Surgery; Female; Gastroenterology; Hepatitis B; Hepatitis B - drug therapy; Hepatitis B - epidemiology; Hepatitis B e antigen; Hepatitis B e Antigens - analysis; Hepatitis B e Antigens - classification; Hepatitis B surface antigen; Hepatitis B virus - pathogenicity; Hepatology; Humans; Logistic Models; Male; Medicine; Medicine & Public Health; Middle Aged; Original Article―Liver; Original ―Liver, Pancreas, and Biliary Tract; Pancreas; Patients; Prospective Studies; Recurrence; Ribonucleic acid; RNA; Surgical Oncology; Treatment Outcome; China; HBcrAg; Virological relapse; Cessation; HBsAg loss; HBV RNA

Background Nucleos(t)ide analogues (NAs) cessation is not widely practiced and remains a controversial, but highly relevant subject in patients infected with hepatitis B virus (HBV). We aimed to explore the related factors for safe NAs cessation. Methods This is a multicenter prospective cohort stud...