ASCENDE-RT: An Analysis of Treatment-Related Morbidity for a Randomized Trial Comparing a Low-Dose-Rate Brachytherapy Boost with a Dose-Escalated External Beam Boost for High- and Intermediate-Risk Prostate Cancer - Rodda, Sree; Tyldesley, Scott; Morris, W. James; Keyes, Mira; Halperin, Ross; Pai, Howard; McKenzie, Michael; Duncan, Graeme; Morton, Gerard; Hamm, Jeremy; Murray, Nevin (International journal of radiation oncology, biology, physics, 2017)
Keywords: Aged; Aged, 80 and over; Androgen Antagonists - adverse effects; Androgen Antagonists - therapeutic use; BRACHYTHERAPY; Brachytherapy - adverse effects; Brachytherapy - methods; Combined Modality Therapy - adverse effects; Combined Modality Therapy - methods; Diarrhea - epidemiology; Diarrhea - etiology; DISEASE INCIDENCE; Disease-Free Survival; Erectile Dysfunction - epidemiology; Erectile Dysfunction - etiology; EXTERNAL BEAM RADIATION THERAPY; Feasibility Studies; Fecal Incontinence - epidemiology; Fecal Incontinence - etiology; Follow-Up Studies; Gastrointestinal Hemorrhage - epidemiology; Gastrointestinal Hemorrhage - etiology; Gonadotropin-Releasing Hormone - adverse effects; Gonadotropin-Releasing Hormone - therapeutic use; GY RANGE 10-100; Hematology, Oncology and Palliative Medicine; Humans; Incidence; Intention to Treat Analysis; Logistic Models; Male; MEN; Middle Aged; NEOPLASMS; Pelvis; PROSTATE; Prostatic Neoplasms - drug therapy; Prostatic Neoplasms - radiotherapy; RADIATION HAZARDS; Radiology; RADIOLOGY AND NUCLEAR MEDICINE; Radiotherapy Dosage; Radiotherapy, Conformal - adverse effects; Re-Irradiation - adverse effects; Re-Irradiation - methods; Rectum - radiation effects; Time Factors; Urinary Incontinence - epidemiology; Urinary Incontinence - etiology; Urination Disorders - epidemiology; Urination Disorders - etiology; Urogenital System - radiation effects